Bioactive Peptides

Focuses on Biology, Pharmacology, and Therapeutic Applications The study and diverse applications of bioactive peptides traverse many sub-disciplines within chemistry, biology, physics, and medicine.

Author: John Howl

Publisher: CRC Press

ISBN: 9780367385736

Category:

Page: 503

View: 373

Focuses on Biology, Pharmacology, and Therapeutic Applications The study and diverse applications of bioactive peptides traverse many sub-disciplines within chemistry, biology, physics, and medicine. Answering a long-standing need, Bioactive Peptides focuses on the biology, pharmacology, and therapeutic applications of endogenous peptide mediators and their analogues. Moving peptide science beyond chemical synthesis strategies and into the realms of peptide biology and therapeutics, it presents the overall contribution that peptide science has made to molecular, cellular, and whole organism biology, while also discussing future targets and therapeutic applications. Beneficial for Experts and Novices Alike Part I provides details of bioactive peptides that interact with common drug targets and analyzes some of the most competitive areas of current research worldwide. While it is widely known that mammalian physiological systems utilize bioactive peptides that have yet to be discovered, other animals provide a rich and valuable source of bioactive peptides. This fascinating area of science is the theme of Part II. Parts III and IV investigate the unique bioactivities of various peptides that are ripe for further exploration. This definitive reference also includes: A detailed description and analysis of a broad range of peptides that interact with G protein-coupled receptors, the quantitatively dominant drug target A discussion of non-ribosomal peptides, which hold promise as sources of endogenous mediators Important examples of common methodologies employed to identify, characterize, and further develop bioactive peptides from a range of natural sources With mounting worldwide interest in their therapeutic potential, bioactive peptides--includ

Bioactive Peptides

Author: John Howl

Publisher: CRC Press

ISBN:

Category: Medical

Page: 479

View: 516

Answering a long-standing need in the pharmaceutical and biotechnology fields, this definitive reference focuses on the biology, pharmacology, and therapeutic applications of endogenous peptide mediators and their analogues. This book takes peptide science beyond chemical synthesis strategies and into the realms of peptide biology and therapeutics. It presents the overall contribution peptide science has made to molecular, cellular and whole organism biology, while discussing future targets and therapeutic applications.

Bioactive Peptides

Features Discusses different methodologies employed for scaling up bioactive peptides commercially Provides information on optimizing the production process Explains various bioactive properties exerted by different types of bioactive ...

Author: John Oloche Onuh

Publisher: CRC Press

ISBN: 1000387534

Category: Technology & Engineering

Page: 508

View: 849

Bioactive peptides have been receiving attention recently due to their applications as health-promoting agents. Derived from food proteins and other natural sources, they exhibit various beneficial effects such as preventing diseases or modulating physiological systems once absorbed. As the market for nutraceuticals and functional foods continues to expand, consumer interest has also grown and there are many common foods that have shown an abundance of bioactive peptides, including dairy products, cereal, legumes, meat, and numerous other sources. In this newest addition to the series Nutraceuticals: Basic Research and Clinical Applications, Bioactive Peptides: Production, Bioavailability, Health Potential, and Regulatory Issues provides a comprehensive review of the current state of knowledge in the field of food protein hydrolysates and bioactive peptides, their food sources, bioavailability, production, applications, functionalities, health potentials, and regulatory issues governing their use. Features Discusses different methodologies employed for scaling up bioactive peptides commercially Provides information on optimizing the production process Explains various bioactive properties exerted by different types of bioactive peptides Explores the application of metabolomics to the study of bioactive peptides With over 20 chapters written by established subject matter experts in their field, this book provides timely information and discusses the latest developments of bioactive peptides. It will be useful for researchers, academics, and industry experts, and can serve as an excellent resource for anyone interested in enhancing their knowledge in the field of bioactive peptides.

Bioactive Peptides in Drug Discovery and Design

Preface This volume is a potpourri of review and research articles related to the "
Bioactive Peptides in Drug Discovery and Design : Medical Aspects ” . Several
topics that cover biophysical , biochemical , physiological and synthetic aspects
of ...

Author: John Matsoukas

Publisher: IOS Press

ISBN: 9789051994254

Category: Medical

Page: 300

View: 665

As in previous editions, the focus in ESSENTIAL MATHEMATICS with APPLICATIONS remains on the Aufmann Interactive Method (AIM). Students are encouraged to be active participants in the classroom and in their own studies as they work through the How To examples and the paired Examples and You Try It problems. Student engagement is crucial to success. Presenting students with worked examples, and then providing them with the opportunity to immediately solve similar problems, helps them build their confidence and eventually master the concepts. Simplicity is key in the organization of this edition, as in all other editions. All lessons, exercise sets, tests, and supplements are organized around a carefully constructed hierarchy of objectives. Each exercise mirrors a preceding objective, which helps to reinforce key concepts and promote skill building. This clear, objective-based approach allows students to organize their thoughts around the content, and supports instructors as they work to design syllabi, lesson plans, and other administrative documents. New features like Focus on Success, Apply the Concept, and Concept Check add an increased emphasis on study skills and conceptual understanding to strengthen the foundation of student success. The Ninth Edition also features a new design, enhancing the Aufmann Interactive Method and making the pages easier for both students and instructors to follow. Available with InfoTrac Student Collections http://gocengage.com/infotrac.

Bioactive Peptides

The earliest groups of bioactive peptides derived from nutritional sources were
short peptide fragments generated by digesting milk casein. Encrypted, bioactive
peptides were also formed as by-products of food fermentation. Literally
hundreds ...

Author: Richard Owusu-Apenten

Publisher: CRC Press

ISBN: 1439813639

Category: Medical

Page: 414

View: 695

Chronic illnesses, injury, or infections produce a decline in muscle massleading to delayed recovery, more post-treatment complications, longer hospital stays, and higher mortality rates. Therefore, ensuring adequate lean body mass is of major concern in health care. Presenting data from human studies and trials, along with recent research findings

Marine Bioactive Peptides Structure Function and Therapeutic Potential

This Special Issue Book, “Marine Bioactive Peptides: Structure, Function, and Therapeutic Potential" includes up-to-date information regarding bioactive peptides isolated from marine organisms.

Author: Tatiana V. Ovchinnikova

Publisher: MDPI

ISBN: 3039215329

Category: Medical

Page: 442

View: 661

This Special Issue Book, “Marine Bioactive Peptides: Structure, Function, and Therapeutic Potential" includes up-to-date information regarding bioactive peptides isolated from marine organisms. Marine peptides have been found in various phyla, and their numbers have grown in recent years. These peptides are diverse in structure and possess broad-spectrum activities that have great potential for medical applications. Various marine peptides are evolutionary ancient molecular factors of innate immunity that play a key role in host defense. A plethora of biological activities, including antibacterial, antifungal, antiviral, anticancer, anticoagulant, endotoxin-binding, immune-modulating, etc., make marine peptides an attractive molecular basis for drug design. This Special Issue Book presents new results in the isolation, structural elucidation, functional characterization, and therapeutic potential evaluation of peptides found in marine organisms. Chemical synthesis and biotechnological production of marine peptides and their mimetics is also a focus of this Special Issue Book.

Bioactive Peptide Grafted Polyurethane Copolymers

ARP 6789 AWB 1735 4675 BIOACTIVE PEPTIDE GRAFTED POLYURETHANE
COPOLYMERS : SYNTHESIS , SURFACE PROPERTIES AND CELL ADHESION
STUDIES Horng - Ban Lin Under the Supervision of Professor Stuart L . Cooper ...

Author: Horng-Ban Lin

Publisher:

ISBN:

Category:

Page: 350

View: 609


Bioactive Peptides Produced by Limited Proteolysis

This book is focused on a particular aspect of protein degradation, namely, limited proteolysis, which gives rise to bioactive peptides as a result of the enzymatic action of proteinases and peptidases, which are enzymes that hydrolyze ...

Author: Antonio Camargo

Publisher: Biota Publishing

ISBN: 1615043691

Category: Medical

Page: 92

View: 457

Proteins are considered supremely important for the organization, survival, and functioning of living organisms. They were considered stable and static molecules until the early 1940s, when RudolphSchoenheimer demonstrated that proteins exist in a constant dynamic process of synthesis and degradation (proteostasis), absolutely essential for life. Since then, general and limited protein degradation became some of the most fascinating aspects of biological sciences. This book is focused on a particular aspect of protein degradation, namely, limited proteolysis, which gives rise to bioactive peptides as a result of the enzymatic action of proteinases and peptidases, which are enzymes that hydrolyze specific peptide bonds of proteins and peptides, respectively. In a broad sense, bioactive peptides are any fragment of endogenous or exogenous proteins able to elicit either physiological or pathological activities. Here, we aim at presenting to the readers that bioactive peptides are not merely produced through random processes during protein degradation, but rather through a well-organized enzymatic process that is deeply integrated in the homeostatic processes of living organisms.

Food Proteins and Bioactive Peptides

This book is a printed edition of the Special Issue "Food Proteins and Bioactive Peptides" that was published in Foods

Author: Maria Hayes

Publisher: MDPI

ISBN: 3038428639

Category: Science

Page: 178

View: 795

This book is a printed edition of the Special Issue "Food Proteins and Bioactive Peptides" that was published in Foods

Neuropeptides and Other Bioactive Peptides

In this review, several decades of research on peptides in cell-cell signaling are summarized, with a focus on neuropeptide discovery, biosynthesis, and function.

Author: Lloyd D. Fricker

Publisher: Morgan & Claypool Publishers

ISBN: 1615045066

Category: Science

Page: 107

View: 715

Neuropeptides and peptide hormones represent the largest class of chemical messengers that transmit information from one cell to another. In this review, several decades of research on peptides in cell-cell signaling are summarized, with a focus on neuropeptide discovery, biosynthesis, and function. In addition to covering the well-studied aspects of neuropeptides, emerging concepts are discussed, including classical versus non-classical neuropeptides and direct versus indirect neuropeptides. Other potential functions for peptides in intercellular and intracellular signaling are also discussed. Table of Contents: Overview of Neuropeptides / Neuropeptide Discovery / Neuropeptide Biosynthesis / Neuropeptides After Secretion: Receptors and Peptidases / Representative Neuropeptides / Concluding Remarks and Future Directions / References / Author Biography

Impact of Bioactive Peptides on Human Health

This book is a printed edition of the Special Issue "Impact of Bioactive Peptides on Human Health" that was published in Nutrients

Author: Kaustav Majumder

Publisher: MDPI

ISBN: 3038976202

Category: Medical

Page: 212

View: 273

This book is a printed edition of the Special Issue "Impact of Bioactive Peptides on Human Health" that was published in Nutrients

Biologically Active Peptides

In the interdisciplinary field of bioactive peptides, this book bridges the gap between basic peptide chemistry and human physiology, while reviewing recent advances in peptide analysis and characterization.

Author: Fidel Toldra

Publisher: Academic Press

ISBN: 9780128213896

Category: Science

Page: 512

View: 876

Biologically Active Peptides: From Basic Science to Applications for Human Health stands as a comprehensive resource on bioactive peptide science and medicine. With contributions from more than thirty global experts, topics discussed include bioactive peptide science, structure-activity relationships, best practices for their study and production, and applications in medicine. In the interdisciplinary field of bioactive peptides, this book bridges the gap between basic peptide chemistry and human physiology, while reviewing recent advances in peptide analysis and production. Methods and technology-driven chapters offer step-by-step guidance in peptide preparation from different source materials, bioactivity assays, analysis and identification of bioactive peptides, encoding bioactive peptides. Later, applications across disease areas and medical specialties are examined in-depth, including the use of bioactive peptides in treating obesity, diabetes, osteoporosis, mental health disorders, food allergies, and joint health, among other disorders, as well as bioactive peptides for sensory enhancement, sports and clinical nutrition, lowering cholesterol, improving cardiovascular health, and driving advances in biotechnology. Discusses the latest advances in bioactive peptide chemistry, functionality and analysis Offers step-by-step instruction in applying new technologies for peptide extraction, protection, production and encoding, as well as employing bioactive peptide sequencing and bioactivity assays in new research Effectively links basic peptide chemistry, human biology and disease Features chapter contributions from international experts across disciplines and applications


Bioactive Peptides

This book reviews the types, roles and recent research of bioactive peptides.

Author: Kathryn Powell

Publisher:

ISBN: 9781536109733

Category:

Page:

View: 725


Formation of Bioactive Peptides from Dairy Products

This Book Provides Detailed Information Of The Formation Of Bioactive Peptides From Dairy Products. It Comprehensively Describes The Medicinal And Nutritional Value Of Primary Classes Of Bioactive Milk Peptides.

Author: Meenakshi Paul

Publisher:

ISBN: 9788189729165

Category: Amino acid sequence

Page: 276

View: 758

Milk Contains Components That Provide Critical Nutritive Elements, Immunological Protection, And Biologically Active Substances To Both Neonates And Adults. Bioactive Peptides Have Been Identified Within The Amino Acid Sequences Of Native Milk Proteins. The Bioactive Peptides Encrypted In Milk Proteins Can Be Released By Enzymatic Proteolysis, Gastrointestinal Digestion, Or Food Processing. Bioactive Milk Peptides Directly Influence Numerous Biological Processes Evoking Behavioural, Gastrointestinal, Hormonal, Immunological, Neurological, And Nutritional Responses. This Book Provides Detailed Information Of The Formation Of Bioactive Peptides From Dairy Products. It Comprehensively Describes The Medicinal And Nutritional Value Of Primary Classes Of Bioactive Milk Peptides. Students And Professionals From The Fields Of Pharmacology, Dairy, Food Science And Biochemistry Will Find This Work Of Utmost Use. Contents Chapter 1: Bioactive Milk Peptides; Chapter 2: Functional Dairy Products; Chapter 3: Dairy Proteins And Bioactive Peptides In Nutrition And Health; Chapter 4: Models Of Bioactive Peptides; Chapter 5: Hypotensive Peptides From Milk Proteins; Chapter 6: Effects Of Milk Peptides On Calcium And Bone Metabolism; Chapter 7: Potentials Of Antimicrobial Peptides; Chapter 8: Medicinal Activity Of Whey Peptides; Chapter 9: Frontier In Soy Bioactive Peptides; Chapter 10: Caseinophosphopeptides And Mineral Bioavailability; Chapter 11: Functional Characterisation Of Protein Hydrolysates; Chapter 12: Therapeutic Proteins And Purification; Chapter 13: Bioactive Factors In Human Milk; Chapter 14: Bioactive Peptides Via Non-Natural, Sequence Specific Peptidomimetic Oligomers.

Bioactive Food Peptides in Health and Disease

Also, the chapters describe the impact of bioactive peptides on the physiological absorption, regulation and disease prevention. The book also covers the recent technological advances for the production of food peptides.

Author: Blanca Hernández-Ledesma

Publisher: BoD – Books on Demand

ISBN: 9535109642

Category: Technology & Engineering

Page: 278

View: 446

"Bioactive Food Peptides in Health and Disease" highlights recent developments on bioactive food peptides for the promotion of human health and the prevention/management of chronic diseases. The book provides a comprehensive revision of bioactive peptides obtained from both animal and plant food sources. Aspects related to their bioactivity, mechanism of action, and bioavailability are extensively described along the different chapters. Also, the chapters describe the impact of bioactive peptides on the physiological absorption, regulation and disease prevention. The book also covers the recent technological advances for the production of food peptides. Bioactive Food Peptides in Health and Disease provides updated and interesting information, being a good reference book for nutritional and food scientists, biochemists, industry producers, and consumers.

Bioactive Food Proteins and Peptides

Academics, food scientists and technologists, nutritionists, biochemists, persons in industry, and government researchers and regulators will find this book to be an essential resource for new data and developments.

Author: Navam S. Hettiarachchy

Publisher: CRC Press

ISBN: 1420093142

Category: Technology & Engineering

Page: 368

View: 952

Many naturally occurring compounds from foods such as rice, vegetables, fruits, and animal products possess properties that help to slow disease progression, inhibit pathophysiological mechanisms, or suppress activities of pathogenic molecules. Proteins and peptides play significant roles in such activities and are gaining importance as nutraceuticals that benefit numerous aspects of health and nutrition. Bioactive Food Proteins and Peptides: Applications in Human Health provides a human health perspective on food-derived proteins and peptides. It describes the potential for large-scale production with advances in technology and proposes challenges and opportunities for the future of health, nutrition, medicine, and the biosciences. The book begins by addressing properties related to chemistry and bioactivity. It examines proteins and peptides as allergens, antihypertensive agents, antimicrobials, antioxidants, and anticancer agents. It also discusses findings on the bioavailability and toxicity of food-derived peptides and intestinal functions. Next, the contributors present information on therapeutic peptides. They discuss recent developments in proteomics, bioavailability, and opportunities for designing future peptide-based foods. Providing a comprehensive review of bioactive proteins and peptides obtained from food sources, the book brings together the most up-to-date and essential information from eminent researchers from all over the world. Academics, food scientists and technologists, nutritionists, biochemists, persons in industry, and government researchers and regulators will find this book to be an essential resource for new data and developments.

Marine Proteins and Peptides

This book is the first to fill that gap.

Author: Se-Kwon Kim

Publisher: John Wiley & Sons

ISBN: 1118375114

Category: Technology & Engineering

Page: 816

View: 982

Food proteins and bioactive peptides play a vital role in thegrowth and development of the body’s structural integrity andregulation, as well as having a variety of other functionalproperties. Land animal-derived food proteins such as collagen andgelatine carry risks of contamination (such as BSE). Marine-derivedproteins, which can provide equivalents to collagen and gelatinwithout the associated risks, are becoming more popular amongconsumers because of their numerous health beneficial effects. Mostmarine-derived bioactive peptides are currently underutilized.While fish and shellfish are perhaps the most obvious sources ofsuch proteins and peptides, there is also the potential for furtherdevelopment of proteins and peptides from sources like algae, seacucumber and molluscs. Marine-derived proteins and peptides alsohave potential uses in novel products, with the possibility of widecommercialization in the food, beverage, pharmaceutical andcosmetic industries, as well as in other fields such asphotography, textiles, leather, electronics, medicine andbiotechnology. Marine Proteins and Peptides: Biological Activities andApplications presents an overview of the current status,future industrial perspectives and commercial trends of bioactivemarine-derived proteins and peptides. Many of the industrialperspectives are drawn from the food industry, but the book alsorefers to the pharmaceutical and cosmetics industries. There haverecently been significant advances in isolating functionalingredients from marine bio-resources and seafood by-products foruse in these industries, but little has been published, creating aknowledge gap, particularly with regard to the isolation andpurification processes. This book is the first to fill thatgap. Marine Proteins and Peptides: Biological Activities andApplications is a valuable resource for researchers inmarine biochemistry field as well as food industry managersinterested in exploring novel techniques and knowledge onalternative food protein sources. It will become a standardreference book for researchers involved in developing marinebio-resources and seafood by-products for novel nutraceutical,cosmetics, and pharmaceutical applications. It will also appeal tomanagers and product developers in the food, pharmaceutical andcosmetics industries, particularly those looking to usemarine-derived proteins and peptides as substitutes or replacementsfor unfashionable or outdated food components.

Bioactive Proteins and Peptides as Functional Foods and Nutraceuticals

The book considers fundamental concepts and structure-activity relations for the major classes of nutraceutical proteins and peptides.

Author: Yoshinori Mine

Publisher: John Wiley & Sons

ISBN: 9780470961742

Category: Technology & Engineering

Page: 436

View: 606

Bioactive Proteins and Peptides as Functional Foods and Nutraceuticals highlights recent developments of nutraceutical proteins and peptides for the promotion of human health. The book considers fundamental concepts and structure-activity relations for the major classes of nutraceutical proteins and peptides. Coverage includes functional proteins and peptides from numerous sources including: soy, Pacific hake, bovine muscle, peas, wheat, fermented milk, eggs, casein, fish collagen, bovine lactoferrin, and rice. The international panel of experts from industry and academia also reviews current applications and future opportunities within the nutraceutical proteins and peptides sector.

In Silico Study of Milk Derived Bioactive Peptides

The present study was focussed on the development of integrated database of bioactive peptides of milk proteins and other resources, in-silico study of the structures, phylogeny and conserved domains of different bioactive peptides.

Author: Shrikant Sharma

Publisher: LAP Lambert Academic Publishing

ISBN: 9783848413959

Category:

Page: 168

View: 384

The present study was focussed on the development of integrated database of bioactive peptides of milk proteins and other resources, in-silico study of the structures, phylogeny and conserved domains of different bioactive peptides. The developed the integrated database of different bioactive peptides viz. antithrombotic, antimicrobial, opioid, immunomodulatory, mineral binding peptides was developed. In present work, the back end of the above stated database was developed into MSAccess then front end is in JSP, JSS and HTML. This database will be helpful to the researchers working on bioactive peptides. It comprises an information associated to bioactive molecules like Gene-ID, common and scientific name etc. and has significant description of biological process, molecular function and cellular component. Subsequently, feasible structures of bioactive peptides were also designed by using homology approach. For this purpose online server of swiss modal, swiss templates along with swiss repository was used