DHEA in Human Health and Aging

Reduced production of DHEA associated with the diseases that accompany aging has led to its use as a nutritional supplement for antiaging, metabolic support, and other purposes.

Author: Ronald Ross Watson

Publisher: CRC Press

ISBN: 1439838844

Category: Medical

Page: 472

View: 299

Reduced production of DHEA associated with the diseases that accompany aging has led to its use as a nutritional supplement for antiaging, metabolic support, and other purposes. While animal studies have clearly shown substantial benefits of DHEA in combating various disease states, the effect of low levels of DHEA in humans is less established, an

All about DHEA

The books are primers that provide basic introductions. Many health books overwhelm people with too much detail and information on the politics of nutrition. FAQs books answer your questions simply and to the point.

Author: Ray Sahelian

Publisher: Avery Publishing Group

ISBN: 9780895298881

Category: Health & Fitness

Page: 90

View: 865

You've probably come across the term FAQs--which stands for Frequently Asked Questions. Avery's FAQs All About Health series deals with the most commonly asked questions about specific health topics with regards to alternative therapies, nutrition, supplementation, herbal remedies, and disease state management. The books are primers that provide basic introductions. Many health books overwhelm people with too much detail and information on the politics of nutrition. FAQs books answer your questions simply and to the point.

The Superhorme Promise

The best-selling authors of The Melatonin Miracle present new evidence that superhormones can control aging, arguing that DHEA and other hormones can boost the immune system, reduce body fat, maintain health, and reverse the aging process.

Author: William Regelson

Publisher: Simon and Schuster

ISBN: 0671010034

Category: Medical

Page: 400

View: 258

Argues that aging is a preventable disease and provides information on the research, benefits, and availability of superhormones.

The DHEA Breakthrough

With this comprehensive, accessible book, you can look forward to a longer, more satisfying, more healthful life! "I've used DHEA in my practice for five years and seen how it can help restore physiologic balance.

Author: Stephen Cherniske

Publisher: Ballantine Books

ISBN: 0307775011

Category: Health & Fitness

Page: 368

View: 641

DO YOU WANT . . . The high energy you enjoyed in your twenties and thirties? Protection against cancer, heart disease, diabetes, and osteoporosis? Renewed sexual appetite and vigor? To beat depression, boost your memory, and handle stress? To lose body fat while building up your lean muscle mass? DHEA can do all this and more! In The DHEA Breakthrough, biochemist Stephen Cherniske gives you all the information you need to take advantage of and maximize the extraordinary properties of this superhormone--safely and effectively. The DHEA Breakthrough contains the easy-to-implement DHEA Plan, including a diet designed for our "paleolithic" bodies, stress reduction techniques, and an exercise program that eases you into the next level of performance, no matter where you are now. With this comprehensive, accessible book, you can look forward to a longer, more satisfying, more healthful life! "I've used DHEA in my practice for five years and seen how it can help restore physiologic balance. That's close to a modern day miracle, and this book describes the breakthrough perfectly." --Jesse Hanley, M.D., Medical Director, Malibu Health and Rehabilitation

Your Guide to Health Anti Aging

Your Guide to Health: Anti-Aging is an essential reference for managing the processes of physical, mental, and emotional aging.

Author: Donald Vaughn

Publisher: Simon and Schuster

ISBN: 1605505943

Category: Family & Relationships

Page: 224

View: 848

While none of us wants to get older, the journey can be a healthier and happier one if we have critical information at our fingertips. Your Guide to Health: Anti-Aging is an essential reference for managing the processes of physical, mental, and emotional aging. Packed with tips on everything from ensuring a sensible diet to staying informed, this easy-to-follow reference teaches you how to age healthfully and gracefully.

Conn s Handbook of Models for Human Aging

... its significance for human health is much less clear than those two agerelated endocrine changes. Here I will refer to DHEA and its sulfate as DHEA(S), ...

Author: Jeffrey L. Ram

Publisher: Academic Press

ISBN: 0128113545

Category: Medical

Page: 1218

View: 938

Conn's Handbook of Models for Human Aging, Second Edition, presents key aspects of biology, nutrition, factors affecting lifespan, methods of age determination, use in research and the disadvantages/advantages of use. Using a multidisciplinary approach, this updated edition is designed as the only comprehensive, current work that covers the diversity in aging models. Chapters on comparative models explore age-related diseases, including Alzheimer's, joint disease, cataracts, cancer and obesity. Also included are new tricks and approaches not available in primary publications. This must-have handbook is an indispensable resource for researchers interested in the mechanisms of aging, gerontologists, health professionals, allied health practitioners and students. Combines both the methods of study for human aging and animal models Provides a historical overview and discussion of model availability, key methods and ethical issues Contains over 200 full color illustrations

Dehydroepiandrosterone DHEA and DHEA Sulfate Roles in Brain Function and Disease

Among the neuroactive steroids, dehydroepiandrosterone (3b-hydroxyandrost-5-ene-17-one, [DHEA]) and its sulfated metabolite DHEA sulfate (DHEAS) have been shown to be potent modulators of neural function, including neurogenesis, neuronal ...

Author: Tracey A. Quinn

Publisher:

ISBN:

Category: Medicine

Page:

View: 941

Among the neuroactive steroids, dehydroepiandrosterone (3b-hydroxyandrost-5-ene-17-one, [DHEA]) and its sulfated metabolite DHEA sulfate (DHEAS) have been shown to be potent modulators of neural function, including neurogenesis, neuronal growth and differentiation, and neuroprotection. Highlighting the potential health significance of DHEA and DHEAS in humans, serum concentrations decrease steadily with age, with lowest concentrations present at the time many diseases of aging and neurodegeneration become apparent. This temporal association has led to the suggestion that pathology associated with cognitive decline, age-related neurological disorders such as Alzheimer's disease, dementia, amyotrophic lateral sclerosis (ALS), and adult onset schizophrenia may, in part at least, be attributed to decreased secretion of DHEA. Animal studies suggest neuroprotective functions for DHEA and DHEAS through reduction of glutamate-induced excitotoxicity. Reduced myelin loss and reactive gliosis after spinal cord injury by DHEA treatment also suggest a role for DHEA in the treatment of white matter pathologies such as multiple sclerosis. In this chapter, we discuss the physiological roles of DHEA and DHEAS in the central nervous system (CNS), their potential as neuroprotective hormones with reference to documented effects on excitotoxicity and oxidative stress, and their anti-glucocorticoid actions during chronic stress. The potential for metabolic derivatives of DHEA, such as estrogens and testosterone on brain function, and their contribution to neurodevelopment and neurodegenerative conditions are also discussed.

Aging and Age related Diseases

The aim of this book is to present the basic data on human ageing as well as on age-related diseases.

Author: Michał Karasek

Publisher: Nova Publishers

ISBN: 9781594544262

Category: Medical

Page: 549

View: 499

Ageing has become a great problem for many countries. Due to world-wide life prolongation the number of people over 6o years old has grown rapidly into a ten percent piece of the world population. The growing age of the world population raises many social, economical, and medical problems. The proportion of people in the economically active age groups to those who are over 65 is constantly decreasing. A major consequence of the increasing numbers of individuals in advanced age groups is increasing numbers of patients suffering from age-related diseases. The aim of this book is to present the basic data on human ageing as well as on age-related diseases.

Anti ageing Medicine

This is where anti-ageing medicine finds its niche. Anti-ageing medicine aims at slowing, arresting, and reversing phenomena associated with ageing by merging biotechnological innovation and engineered solutions.

Author: Astrid Stuckelberger

Publisher: vdf Hochschulverlag AG

ISBN: 3728131954

Category: Aging

Page: 304

View: 194

The 21st century technological development is revolutionizing medicine and health care, bringing new hopes to human suffering by offering cures and treatments which were unthinkable a few decades ago. This is where anti-ageing medicine finds its niche. Anti-ageing medicine aims at slowing, arresting, and reversing phenomena associated with ageing by merging biotechnological innovation and engineered solutions. Ideally, by means of the newest medical technology, the "body machinery" should be kept fit and at peak performance all life long. Early detection of age-related dysfunction should thus be "fixed" at any age with interventions such as metabolic fine tuning, enhancement, regeneration, restoration or replacement of "body parts" (i.e. organs, skin, bone or muscle). It covers a vast array of domains: from cell therapy to pharmaceutical interventions, from bio-surgery to aesthetic surgery, from human enhancement to fortified food, from smart housing and robots to toxic-free environments. Anti-ageing medicine holds promises but also significant risks and safety issues which are addressesd in this book. It presents the latest scientific evidence on what works or does not work. It also provides public policy recommendations to ensure the protection of consumers and their rights while encouraging research and development. This book is intended for academics, health professionals, business persons, consumers and policy-makers interested in the latest evidence and ethical issues about anti-ageing medicine.

Longevity and Quality of Life

Early detection can help save lives, as well. Health and longevity of life will ultimately end as a political issue. What is needed is long-term government investments necessary for a viable health policy.

Author: Robert N. Butler

Publisher: Springer Science & Business Media

ISBN: 1461542499

Category: Medical

Page: 321

View: 562

Nations around the world are experiencing a spectacular increase in longevity. Society as a whole is being challenged by issues arising from this revolution in longevity. Although the specter of the loneliness and existential suffering of older citizens is such that some people under the age of 65 find it difficult to conceive of a long-term future, persons over 85 have proven that aging does not necessarily preclude a healthy and productive life. Extraordinary progress in both curative and preventive medicine justifies optimism about the quality of life and state of well-being that can be enjoyed even in great old age. We should look to professionals in diverse fields to develop creative solutions to the inevitable issues that will arise with aging. Governments must prepare for the future health of their citizens by making long-term investments to educate all sectors of society in the value of good nutrition, exercise, and lifestyles that enhance well-being throughout life. Also, governments should realize that the main cause of health care expenditure is serious illness which occurs in persons of all ages, and not predominantly in older people. Early detection can help save lives, as well. Health and longevity of life will ultimately end as a political issue. What is needed is long-term government investments necessary for a viable health policy. The question arises: will world leaders be able to commit to such a policy? Two major socioeconomic phenomena may have a regulating effect on this issue. The first is the emergence of pressure groups that have come into being in response to a particular health issue, such as AIDS. The second is the emergence of ethics committees in developed nations that deal solely with health issues.

Life Beyond 100

No longer. C. Norman Shealy, M.D., Ph.D., whom Caroline Myss calls a "wizard-genius-scientist-mystic-physician," offers Life Beyond 100: Secrets of the Fountain of Youth.

Author: C. Norman Shealy

Publisher: Penguin

ISBN: 1440649898

Category: Health & Fitness

Page: 272

View: 812

Using today's most leading-edge therapies and breakthroughs in the science of longevity, C. Norman Shealy, one of the pioneering holistic physicians of our time, shows how we can healthfully age to one hundred, and beyond. The idea of living well beyond one hundred years-and enjoying those years in good health-used to be the stuff of science fiction. No longer. C. Norman Shealy, M.D., Ph.D., whom Caroline Myss calls a "wizard-genius-scientist-mystic-physician," offers Life Beyond 100: Secrets of the Fountain of Youth. In this deeply learned and revolutionary book, Dr. Shealy provides a new concept of longevity, one that reveals that we can live far longer than current science suggests. Basic healthy living and the use of alternative therapies have long been touted as "the way" to well-being, but Dr. Shealy takes these tenets a step further. From the physiology of stress and its effect on the human mind and body to the importance of DHEA; from the proven techniques of photostimulation and biofeedback training to groundbreaking suggestions for alleviating depression; from Shealy's electromagnetic framework of life to his recommendations for optimal health, Life Beyond 100 presents a detailed roadmap to achieve healthy aging-or "youthing." The result of years of clinical practice and cutting-edge research, Life Beyond 100 also exposes the fallacies behind many of the claims made by the medical establishment and the pharmaceutical industry. Shealy argues that rather than increasing people's life expectancy, these two groups create the opposite effect, consigning hundreds of thousands of people to an often miserable and premature old age by treating symptoms with an antidote-prescription medicine-that is often worse than the ailment itself. As a counterpoint, Life Beyond 100 provides the most ambitious- yet medically grounded and commonsensical-longevity program available. Easy to follow and supported by advanced research, Dr. Shealy's guide to uncovering the secrets of youthful aging redefines the concept of human longevity and offers a new vision of healthy living to one hundred and beyond.

Dhea

Rita Elkins, MH, discusses this hormone's various applications, its most recent research, its safety, and how it can ultimately slow the aging process and promote excellent health.

Author: Rita Elkins

Publisher: Woodland Publishing

ISBN: 9781885670335

Category: Health & Fitness

Page: 32

View: 310

The emergence of new research concerning the body's hormones has pinpointed DHEA as key to maintaining various metabolic processes, endocrinal mechanisms, and reproductive capabilities. Rita Elkins, MH, discusses this hormone's various applications, its most recent research, its safety, and how it can ultimately slow the aging process and promote excellent health.

Aging Without Growing Old

Dr. Yen says, “DHEA is a drug that may help people age more gracefully.”13 Rejuvenates the human body A fall in DHEA levels seems to be related to many ...

Author: Judy Lindberg McFarland

Publisher: Charisma Media

ISBN: 088419969X

Category: Health & Fitness

Page: 516

View: 177

Most people today are aging too rapidly and are dying from illnesses that could be prevented! Judy Lindberg McFarland wants to help readers prevent all the degenerative diseases and illnesses that accompany aging and the heartaches resulting from the loss of one's health.In Aging Without Growing Old, men and women of all ages will find out how to become healthy through natural and nutritional means. They'll learn how to enjoy greater health no matter how old they are and how to slow the aging process down to a crawl. It is possible to start defying your age with the essential information found in this book!

Aging in Nonhuman Primates

DHEA and DHEAS plasma levels decline substantially with age [76–78]. ... Nevertheless, DHEA in humans has been reported to have cardioprotective and ...

Author: Joseph Erwin

Publisher: Karger Medical and Scientific Publishers

ISBN: 380557312X

Category: Science

Page: 239

View: 199

As the number of elderly people in human populations increases, the study of normal aging, age-related disorders, and enhanced longevity is taking on new urgency. Fundamental research will provide means of preventing and effectively treating the most debilitating and distressing aspects of advanced age. Considerations of aging in nonhuman life forms do not aim at life extension, but at an increasing appreciation for the biological role of the aging process in populations, in addition to developing a more comprehensive understanding of the mechanisms of aging. The present volume focuses on primate aging because human characteristics that evolved during their evolution are homologous with those of other primates. Therefore, the research on nonhuman primates will decidedly also contribute to our understanding of the process of human aging. The topics of this volume include brain aging and neurodegenerative diseases, social behavior, cognition and aging, skeletal aging in natural and captive conditions, and consequences of caloric restriction for life and health extension. The great variety of contributions aim at providing a survey of the relevant work in progress and increasing the understanding of normal and pathological aging and life-span enhancement in a variety of nonhuman primate species.

Dehydroepiandrosterone

Dehydroepiandrosterone, Volume 108, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this ...

Author: Gerald Litwack

Publisher: Academic Press

ISBN: 0128143622

Category: Science

Page: 459

View: 895

Dehydroepiandrosterone, Volume 108, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics such as Dehydroepiandrosterone Research: Past, Current and Future, Astrocyte Neuroprotection and Dehydroepiandrosterone, Mutation of HSD3B2 Gene and Fate of Dehydroepiandrosterone, Autophagy and Autophagic Cell Death: Uncovering New Mechanisms Whereby Dehydroepiandrosterone Promotes Beneficial Effects on Human Health, Dehydroepiandrosterone and Cardiovascular Disease, Dehydroepiandrosterone and Experimental Osteoarthritis, The Role of Dehydroepiandrosterone (DHEA) in Skeletal Muscle, Mechanism of Action of Dehydroepiandrosterone, and more. Focuses on the newest aspects of hormone action in connection with diseases Lays the groundwork for the focus of new chemotherapeutic targets Represents reviews on emerging areas in hormone action, cellular regulators and signaling pathways

Assessments Treatments and Modeling in Aging and Neurological Disease

Dehydroepiandrosterone sulfate: A biomarker of primate aging slowed by calorie ... Aging in rhesus monkeys: Relevance to human health interventions.

Author: Colin R. Martin

Publisher: Academic Press

ISBN: 0128180013

Category: Medical

Page: 606

View: 364

Assessments, Treatments and Modeling in Aging and Neurological Disease: The Neuroscience of Aging is a comprehensive reference on the diagnosis and management of neurological aging and associated disorders. The book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the interactions between genetics, epigenetics and other micro-environmental processes. It also examines pharmacological and non-pharmacological interventions of age-related conditions that affect the brain, including Alzheimer’s, stroke and multiple sclerosis. Provides the most comprehensive coverage of the broad range of topics related to the neuroscience of aging Features sections on diagnosis and biomarkers of neurological aging, Alzheimer’s and stroke Contains an abstract, key facts, a mini dictionary of terms, and summary points in each chapter Focuses on neurological diseases and conditions linked to aging, environmental factors and clinical recommendations Includes more than 500 illustrations and tables

The Aging Skeleton

DHEA(S) has been shown to influence serum IGF-I levels in humans [95]. ... the ratio of DHEA(S) to cortisol biosynthesis varies widely in human health and ...

Author: Clifford J. Rosen

Publisher: Elsevier

ISBN: 0080542379

Category: Medical

Page: 642

View: 886

The Aging Skeleton is a comprehensive and timely book on all aspects of the skeleton as it ages, including basic mechanisms and pathways as well as pathobiology. Chapters cover general aspects and models of aging, determinants and maintenance of peak bone mass, mechanisms of age-related bone loss, quantifiable manifestations of age-related bone loss, fractures, and therapeutics. Covers all aspects of the aging skeleton in one comprehensive volume Looks at the influence of genetics, nutrition, environment, hormones, and other factors on bone mass Provides a thorough discussion of fractures, one of the major consequences of the aging skeleton Reviews current therapeutic approaches and methods Written by internationally renowned authors and edited by leaders in the field Is the only book available on this subject

Healthy Aging and Nutrition

Though DHEA levels do decline as people age , research does not support these health claims . Until further research is carried out , DHEA is not ...

Author: United States. Congress. Senate. Special Committee on Aging

Publisher:

ISBN:

Category: Aged

Page: 226

View: 962


Degenerative Diseases of Ageing

properties of DHEA during the last 50 years , yet only in the 1980s did a reasonably clear picture of DHEA's role emerge in human health and physiology .

Author: Vincent Icheku

Publisher: De-Ichekus (UK) Co. Ltd

ISBN: 9780955351006

Category: Aging

Page: 247

View: 973

The capacity to enjoy life well into your old age is sometimes denied by all kinds of degenerative diseases. Regrettably, the information you need to enable you to prevent these diseases is found in hundreds of scientific papers that are not easily accessible to the general public. The result is that most people suffer from these diseases and die prematurely while knowledge of how to prevent or cure their condition already exists. For the first time, the work of many world scientists concerned with the causes and preventions of degenerative diseases of ageing have been put together in a single book, and I hope you will find it useful in your quest for good health and an increased life span.

Magnesium in Human Health and Disease

Health Promotion and Aging: The Role of Dehydroepiandrosterone (DHEA). Harwood Academic Publishers, 1999, 164 pages). For 30 years he was funded by Wallace ...

Author: Ronald Ross Watson

Publisher: Springer Science & Business Media

ISBN: 1627030433

Category: Medical

Page: 309

View: 387

Magnesium is an essential mineral which is required for growth and survival of humans. Since magnesium is a mineral and not synthesizable it must be obtained through dietary foods and/or supplements. Magnesium in Human Health and Disease reviews the benefits of magnesium supplementation to reach recommended intakes as well as provides new research that suggests how reaching levels above the recommended intakes can promote health and treat various diseases. Magnesium deficiency can cause low serum potassium and calcium levels, retention of sodium, and low circulating levels of regulatory hormones. These changes in nutrients cause neurological and muscular symptoms such as tremor and muscle spasms. Further magnesium deficiency causes loss of appetite, nausea, vomiting, personality changes and death from heart failure. Causes of magnesium deficiency include alcohol abuse, poorly controlled diabetes, excessive or chronic vomiting and/or diarrhea. Thus the effects of inadequate and deficient intakes or levels of magnesium is critical to health and are reviewed by the expert clinicians in this book. Magnesium in Human Health and Disease provides the most current research to support the potential benefits or lack thereof for normal and high supplementation with magnesium. Animal model research and early human trials are reviewed to document other disease states such as hypertension, cholesterol level, type 2 diabetes and cardiovascular disease that would benefit from increased magnesium.