Handbook of Clinical Toxicology of Animal Venoms and Poisons

KIRSCHBAUM, N. E., RECZKOWSKY, R.S., AND BUDZINSKY, A.Z., Secretion of cellular plasminogen activators upon stimulation by Crotalinae snake venoms, in Hemostasis and Animal Venoms, Pirkle, H., and Markland, F.S., Eds., New York; ...

Author: Julian White

Publisher: CRC Press

ISBN: 1351443143

Category: Medical

Page: 768

View: 764

The Handbook of Clinical Toxicology of Animal Venoms is the first concise, one-volume book devoted to this important subject. The editors are internationally recognized authorities in the biology and clinical aspects of venomous and poisonous animals, and the chapter authors are world leaders in their respective fields of toxicology. All aspects of the topic are covered including information on the biology and taxonomy of poisonous animals, their venom or poison, diagnosis, and general treatment principles and specific treatment. The most up-to-date list of available antivenoms is provided. Coverage of venomous and poisonous animals is comprehensive, with thorough discussions on shellfish poisoning, ciguatera, fugu, coelenterates, stingrays, venous fish, blue-ringed octopus, sea-snakes, scorpions, spiders, insects, and gila lizards. Individual chapters focus on snakes and snakebite in Europe, Africa, Asia, Australia, North America, Central America, and South America. Nearly all clinical chapters have been written by clinicians with extensive experience treating the particular type of animal envenoming or poisoning under consideration. No other book brings together such a wealth of information in this field, and no other book provides it in a format useful to clinicians charged with the responsibility of treating envenomed or poisoned patients. The Handbook of Clinical Toxicology of Animal Venoms is an essential addition to all medical libraries, emergency departments, toxicology departments, poison information centers, and invaluable to all professionals working in these fields.

Handbook of Toxinology

Peruvian bushmaster snake Lachesis muta , In : Hemostasis and Animal Venoms , H. Pirkle and F.S. Markland ( Eds . ) , p . 107 , Marcel Dekker , New York ( 1988 ) . 175. Shainoff , J.R. , and Welches , W.R. , Studies of the preferential ...

Author: W. T. Shier

Publisher: CRC Press

ISBN: 100010446X

Category: Medical

Page: 872

View: 178

Organized primarily around the mechanisms of action of the toxins at the biochemical, physiological and pathological level, rather than by source, the handbook covers most toxins which have been clearly identified and characterized, but emphasizes toxins that are more important by virtue of the sign

Handbook of Natural Toxins

Reptile Venoms and Toxins Anthony Tu. Bowie, E. J. W., Owen, C. A., Jr., and Giles, A. R. (1989). Animal models for the study of factor VIII and von Willebrand factor. In Coagulation and Bleeding Disorders, T. S. Zimmerman and Z. M. ...

Author: Anthony Tu

Publisher: Routledge

ISBN: 1351442287

Category: Medical

Page: 832

View: 137

In 24 contributed chapters, 37 international specialists describe the latest developments in research on snake venom including different types of venoms and toxins, actions, antidotes, and applications and summarize what is known to date on Gila monster and frog toxins. Some 70 tables provide essent

Fibrinogen Thrombosis Coagulation and Fibrinolysis

Ortiz, F. A., and Gubensek, F., 1976, Isolation and some properties of blood clotting enzyme from the venom of Bothrops ... in Hemostasis and Animal Venoms, Pirkle, H. and Markland, F. S., Jr., eds., Marcel Dekker, Inc., New York, p.

Author: Chung Yuan Liu

Publisher: Springer Science & Business Media

ISBN: 1461538068

Category: Medical

Page: 450

View: 116

The International Scientific Symposium on Fibrinogen, Thrombosis, Coagulation, and Fibrinolysis was held in Academia Sinica, Taipei, Taiwan, Republic of China, on August 30 - September 1, 1989. This Symposium has provided a forum for the free exchange of information in this important and rapidly advancing research field. This proceedings volume provides a published record of 46 papers presented at the Symposium. The sponsors have exerted no influence on the scientific opinions or positions of the participants in the Symposium. It is hoped that this Symposium will stimulate further worldwide cooperation and collaboration in these vital fields for the benefit of all human kind. This volume is composed of four parts. The first part consists of 8 papers on Fibrinogen and Fibrin: Biochemistry, Molecular Biology, and Physiology. The second part contains 16 papers on Coagulation and Fibrinolysis: Biochemistry, Molecular Biology, and Physiology. The third part has 10 papers on Cardiovascular Cell Biology: Biochemistry, Molecular Biology, and Physiology. The fourth part comprises 12 papers on Clinical Studies of the Cardiovascular System: Thrombotic and Bleeding Disorders and Thrombolytic Therapy. The Author Index with addresses of all contributors and the Subject Index of all 46 papers are arranged at the end of this volume.

Toxins and Hemostasis

hemostasis, 2 in animals, development of research tools/therapeutic agents, 2 animal venoms, ... 597 serine proteases, 597 snake venom serine and metalloproteases, 597 Blood coagulation factor IX/factor X binding protein Ca2+-binding ...

Author: R. Manjunatha Kini

Publisher: Springer Science & Business Media

ISBN: 9048192951

Category: Medical

Page: 797

View: 846

Circulation of blood is vital for the survival of vertebrates, including man. Mainly, it plays an important role in carrying food nutrients and oxygen to every tissue and organ and in removing all waste products and carbon dioxide. Any imbalance in the hemostatic and cardiovascular systems can lead to death and severe debility. A number of animals have developed mechanisms to target these systems and exploit the vulnerability. In some species (for example, snakes), such mechanisms are used to immobilize and kill the victim/prey, whereas in others (for example, insects, such as leaches, mosquitoes and ticks), they are used to provide a continuous supply of blood. These mechanisms include, but are not limited to, procoagulant and anticoagulant actions that affect the coagulation cascade and platelet aggregation, as well as altering vasodilatory responses. In all these various animals, these mechanisms have evolved to perfection over millions of years to support their survival. In last 3-4 decades, due to the efforts of scientists from various backgrounds including biology, protein chemistry, molecular biology, pharmacology, hematology, and structural biology, significant progress in understanding the structure-function relationships, as well as the mechanism of action have been made in a number of exogenous factors that affect blood coagulation, platelet aggregation and vasodilation from various animals. These exogenous factors have contributed significantly to the development of research tools as well as providing new therapeutic agents. With the increase average age of the population coupled with changes in life style in recent years, there has been a significant increase in cardiovascular and hematological disorders. Thus scientists in both academic institutions as well as the pharmaceutical industry are developing better therapeutic agents to improve the quality of life. This impetus has lead to the search for novel agents from various sources that interfere with cardiovascular and hematalogical processes. Although at first glance exogenous factors appear to function as ‘villains’, several life-saving drugs have been developed based upon these factors. Such drugs or drug leads include those that inhibit the angiotensin converting enzymes (Captopril and Enalapril), that block platelet receptors (Eptifibatide and Tirofiban), or that digest thrombotic plugs (Alfimeprase and bat plasminogen activator) to name a few. Several new and exciting success stories are currently unfolding. In this book, recent studies on some of the exogenous factors that play crucial roles in cardiovascular and hematological disorders are reviewed in order to consolidate the efforts in this area of research and to recruit new, talented researchers. The 25-30 review chapters, each written by experts in their field, compiled herein are devoted to exogenous factors affecting platelet aggregation, anticoagulant and procoagulant proteins, fibrinolytic proteins and hypotensive agents (For details see, Contents of the Book). This book is intended to help to create elevated awareness and enthusiasm in the field of exogenous factors. I believe that this book will provide greater impetus to the search for novel proteins based on naturally occurring exogenous factors. This will be the first book dealing extensively with exogenous factors in the last 25 years. The book will provide a ready reference to the different approaches used to solve complex problems in protein chemistry and pharmacology of exogenous factors. The book will update our understanding of the structure-function relationships and mechanisms of action of exogenous factors and provide great insights into future directions for solving the remaining challenges.

National Library of Medicine Current Catalog

7 see and animal venoms see Helmont , Jean Baptiste Helmont , van , 1577-1644 van , 1577-1644 Hemostasis Helmrich , Hermann E. ( Hermann Ernst ) . Die Bindegewebsmassage : Lehrbuch über Basis , Technik , Methodik und Praxis der ...

Author: National Library of Medicine (U.S.)



Category: Medicine


View: 855

Medical Use of Snake Venom Proteins

This fascinating book provides actual knowledge on evolution, anatomy habits, and classification of venomous snakes.

Author: Kurt F. Stocker

Publisher: CRC Press

ISBN: 9780849358463

Category: Medical

Page: 280

View: 267

This fascinating book provides actual knowledge on evolution, anatomy habits, and classification of venomous snakes. It presents detailed, updated information on physicochemical, biochemical, and pharmacological characteristics of biomedically relevant snake venom proteins, their practical use and potential. This volume includes particular sections concerning neurotoxins and their application in neurophysiological and muscular research, snake venom proteins affecting the complement system, as well as the large field of snake venom components affecting the hemostatic and fibrinolytic system. Written in a comprehensive manner, this work communicates to the reader the importance of preventing the extinction of venomous snake species as the carriers of unique genetic information. This interesting book is a must for all who are involved with thrombosis, hemotology, toxinology, neurochemistry, as well as animal toxins within biological, medical or pharmaceutical education.

Hemostasis and Thrombosis

Outany C , Yun Yang F : The effects of the purified thrombin - like enzyme and anticoagulant principle of Trimeresurus gramineus venom on blood coagulation in vivo . Toxicon 14 ( 3 ) : 197-201 , 1976 ANIMAL / * ANTICOAGULANTS ...




Category: Blood


View: 161

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