Hypertension in Kidney Disease

Blood pressure control is central to all bodily functions. There are many points in the multifaceted cybernetic system wherein hypertension may be produced.

Author: J.S. Cheigh

Publisher: Springer Science & Business Media

ISBN: 9400942710

Category: Medical

Page: 312

View: 395

Blood pressure control is central to all bodily functions. There are many points in the multifaceted cybernetic system wherein hypertension may be produced. Hypertension is a 'young' disorder whose existence has been known for less than a century. It is not only extremely prevalent among every popula tion, but also deleterious to the health of mankind. The more we understand about hypertension's harmful effects, the more urgent is the need for its effective control. The kidney is the central organ that controls vascular tone and body fluid volume; these two factors are dominant in determining arterial blood pres sure. Hence, it is not surprising to find in hypertensive disorders that there are abnormalities in the kidneys, functional or anatomical, subtle or overt, that cause or are the consequence of hypertension. The first suggestion that the kidney could cause hypertension was made in 1836, before arterial pressure could even be measured, by Richard Bright. He observed that cardiac hypertrophy was often present in patients who died of renal disease. It was, however, Goldblatt and his colleagues in 1934 who opened the modern era of experimental and clinical research in renal hypertension. Since then, although far from complete, enthusiastic and intensive research efforts have greatly improved our understanding of the nature of renal hypertension.

Hypertension and Kidney Disease ECAB

This book aims to guide the practitioner to diagnose and manage hypertension in the setting of suspected, diagnosed, or established kidney disease with special reference to practical experience in India.

Author: Suresh C Tiwari

Publisher: Elsevier Health Sciences

ISBN: 8131231976

Category: Medical

Page: 152

View: 822

Hypertension is fast becoming a pandemic of enormous proportions, and its sequelae of cardiovascular and cerebrovascular adverse events is making it a leading cause of morbidity and mortality worldwide. The interrelationship of hypertension and kidney changes though established for quite some time, the exact mechanisms and causality are still being discovered. The role of kidney as evidenced by subtle changes in the initiation of ‘primary hypertension’ is increasingly being scrutinized. The effects of established renal causes that induce hypertension such as renal artery stenosis are well established. Pediatric population is also no longer immune to this potentially debilitating condition. This book will help the readers to: Understand the intricacies of the genesis of hypertension and its effects on the kidney Explore the various established guidelines and newer promising aspects in diagnosis and management of hypertension and the kidney changes Know the newer emerging concepts in the treatment of hypertension in the pediatric population Enlighten them about the benefits of timely management of the condition to prevent its progression to end-stage kidney disease, which requires expensive and invasive interventions not suitable to majority of population in a developing country like ours. This book aims to guide the practitioner to diagnose and manage hypertension in the setting of suspected, diagnosed, or established kidney disease with special reference to practical experience in India.


Kidney in Essential Hypertension

The kidney, similar to the heart, plays a three-fold role in essential hypertension. First, it participates in the patho genesis of arterial hypertension.

Author: Franz H. Messerli

Publisher: Springer Science & Business Media

ISBN: 1461338972

Category: Medical

Page: 260

View: 288

The kidney, similar to the heart, plays a three-fold role in essential hypertension. First, it participates in the patho genesis of arterial hypertension. Second, it suffers as a target organ of long-standing hypertension, and third, it experiences the effects of antihypertensive therapy. Perhaps most contested at the present time is the involvement of the kidney in the patho genesis of essential hypertension. More than a century ago, William Osler put forward three basic hypotheses about the "genuine contracted kidney. "l 1. "The hypertrophy can be regarded as an effect to overcome a sort of stop-cock action of the vessels when under the influence of an irritating ingredient in the blood greatly contracted and increased the peripheral resistance. " Clearly this hypothesis of an "irritating ingredient" is perhaps the most convincing nowadays, and numerous attempts have been made to identify a specific vasoconstrictive agent in the blood in essential hypertension. 2. "The obliteration of a large number of capillary territories in the kidney materially raised the arterial pressure. An additional factor of dimin ished excretion of water also heightened the pressure within the blood vessel. " Today we know that fluid volume overload in the presence of reduced renal mass seems to be the most likely mechanism accoun ting for renal parenchymal hypertension and, as shown by Guyton's group, for certain forms of experimental hypertension. 3.

National High Blood Pressure Education Program NHBPEP Working Group Report on Hypertension and Chronic Renal Failure

Reviews the current knowledge of the interaction of elevated blood pressure, hemodynamics, and renal damage, and presents the clinical recommendations of the NHBPEP Working Group.

Author: National High Blood Pressure Education Program. Working Group on Hypertension and Chronic Renal Failure

Publisher:

ISBN:

Category: Chronic renal failure

Page: 20

View: 279

Reviews the current knowledge of the interaction of elevated blood pressure, hemodynamics, and renal damage, and presents the clinical recommendations of the NHBPEP Working Group.

Renovascular and Renal Parenchymatous Hypertension

The book also covers topics such as the value of medical therapy, surgical techniques, and percutaneous transluminal angioplasty, with special reference to the treatment of renal hypertension.

Author: Thomas Luescher

Publisher: Springer Science & Business Media

ISBN: 3642612393

Category: Medical

Page: 574

View: 537

This monograph provides a timely update on the pathophysiology, diagnosis, and therapy of renovascular and renal parenchymatous hypertension. The underlying causes of the most common forms of hypertension are discussed in separate chapters. Special emphasis is laid on newer pathophysiological aspects of the disease, in particular the vascular wall renin-angiotensin system. Furthermore, there is in depth discussion of all the new techniques that are currently available for use in the diagnosis of renal hypertension, e.g., ultrasound and Doppler techniques, magnetic resonance imaging, and nuclear renography. These techniques are discussed by internationally renowned experts in the field. The book also covers topics such as the value of medical therapy, surgical techniques, and percutaneous transluminal angioplasty, with special reference to the treatment of renal hypertension.


Core Concepts in Hypertension in Kidney Disease

This guide provides a comprehensive review of the full spectrum of hypertension in chronic kidney disease (CKD).

Author: Ajay K. Singh

Publisher: Springer

ISBN: 1493964364

Category: Medical

Page: 349

View: 932

This guide provides a comprehensive review of the full spectrum of hypertension in chronic kidney disease (CKD). Targeted towards the busy practitioner, the focus of this volume is on various therapies and how to lower blood pressure through lifestyle changes. Specialist patient populations and hypertension and causes of hypertension are also covered in detail. Clinically-focused and authoritative, this resource offers a rationalized approach to diagnosing and treating hypertension in CKD.


Kidney and Blood Pressure Regulation

This book reviews experimental data which form the basis of our current understanding of the association between hypertension and kidney diseases: The pathogenesis of increased blood pressure, the mechanisms by which systemic hypertension ...

Author: Hiromichi Suzuki (M.D.)

Publisher: Karger Medical and Scientific Publishers

ISBN: 3805577516

Category: Medical

Page: 172

View: 244

Chronic kidney disease is one of the world's major public health problems, and the prevalence of kidney failure is rising steadily. Among the risk factors for a faster progression of renal disease are hypertension and proteinuria, many studies clearly demonstrating that hypertension is both a cause and consequence of chronic kidney disease. Namely, renal blood pressure regulation seems to be involved in five major pathophysiological mechanisms (all closely related to the renin-angiotensin system): Pressure-natriuresis, renal sympathetic nervous system, renal blood flow, intraglomerular pressure and tubuloglomerular feedback. This book reviews experimental data which form the basis of our current understanding of the association between hypertension and kidney diseases: The pathogenesis of increased blood pressure, the mechanisms by which systemic hypertension promotes progressive kidney failure, and the impact of antihypertensive agents on experimental renal mechanisms involved in hypertension. Furthermore, the role of angiotensin II receptor blockers in both the control of systemic blood pressure and the reduction of proteinuria is examined in an attempt to define optimal therapeutic strategies to prevent the otherwise inexorable deterioration of renal function in patients with chronic kidney disease.