Metal Carbenes in Organic Synthesis

Kaum eine Stoffklasse läßt sich vielseitiger in der organischen Synthese nutzen als Carbenkomplexe.

Author: Florencio Zaragoza Dörwald

Publisher: John Wiley & Sons

ISBN: 3527614079

Category: Science

Page: 290

View: 941

There are hardly more versatile compounds in organic synthesis than carbene complexes. The rapid development of new synthetic methods involving carbene complexes - stereoselective cyclopropanation, carbonyl olefination, olefin metathesis, etc. - reveals the value and high potential of these compounds. Their application ranges from the synthesis of fine chemicals to polymer production. This comprehensive, well structured handbook presents the fundamental principles and the recent advances in carbene complex chemistry. Arranged according to structure and reactivity, all relevant classes of carbene complexes, their generation, and application in organic synthesis are discussed in detail. Critically selected, up-to-date references and valuable experimental procedures await the reader. Every chemist searching for a concise introduction and reference work for carbene complex chemistry will welcome this practical guide. "...this concise presentation of all the aspects of the use of carbene complexes in synthesis will help provide the impetus for even more rapid developments in this field of research." R. H. Grubbs (Caltech)

Metal Carbenes in Organic Synthesis

Every chemist searching for a concise introduction and reference work for carbene complex chemistry will welcome this practical guide. "...this concise presentation of all the aspects of the use of carbene complexes in synthesis will help ...

Author: Florencio Zaragoza Dörwald

Publisher: Wiley-VCH

ISBN: 9783527296255

Category: Science

Page: 290

View: 315

There are hardly more versatile compounds in organic synthesis than carbene complexes. The rapid development of new synthetic methods involving carbene complexes - stereoselective cyclopropanation, carbonyl olefination, olefin metathesis, etc. - reveals the value and high potential of these compounds. Their application ranges from the synthesis of fine chemicals to polymer production. This comprehensive, well structured handbook presents the fundamental principles and the recent advances in carbene complex chemistry. Arranged according to structure and reactivity, all relevant classes of carbene complexes, their generation, and application in organic synthesis are discussed in detail. Critically selected, up-to-date references and valuable experimental procedures await the reader. Every chemist searching for a concise introduction and reference work for carbene complex chemistry will welcome this practical guide. "...this concise presentation of all the aspects of the use of carbene complexes in synthesis will help provide the impetus for even more rapid developments in this field of research." R. H. Grubbs (Caltech)


New Aspects of Zirconium Containing Organic Compounds

This volume organized in eight chapters written by the leading scientists in the field illustrates the theoretical background, non-classical nucleophilic and cycloaddition patterns, chromium-templated benzannulation and photo-induced ...

Author: Ilan Marek

Publisher: Springer Science & Business Media

ISBN: 9783540222217

Category: Science

Page: 175

View: 404

Metal carbene complexes have made their way from organometallic curiosities to valuable reagents and catalysts. They offer novel synthetic opportunities in carbon-carbon bond formation based on either carbene-centered reactions or on metal-templated processes which makes them indispensable in modern synthetic methodology. The most prominent metal carbenes are now either commercially available or easy to synthesize and handle with modern laboratory techniques. This volume organized in eight chapters written by the leading scientists in the field illustrates the theoretical background, non-classical nucleophilic and cycloaddition patterns, chromium-templated benzannulation and photo-induced reactions, rhodium-catalyzed carbene transfer as well as the principles and applications of olefin metathesis which has coined the progress in synthetic methodology over the past decade. Designed for researchers in academia and industry as well as graduate students it presents the state-of-the-art potential of carbene complexes in modern organic synthesis.

First Row Transition Metal Carbenes from Supporting Ligands to Organic Reactive Fragments

In the organometallic field, the synthesis of a novel ligand bearing a chelating scaffold and a mesoionic carbene moiety has allowed the preparation of a family of first row transition metal complexes.Using carbenes as intermediates in ...

Author: Mònica Rodríguez Serrat

Publisher:

ISBN:

Category:

Page: 160

View: 390

In the last decades, carbenes have shown a huge potential and versatility in organometallic and organic chemistry. In each of these fields, first row transition metal chemistry is less developed than noble metal complexes. In the pursuit of more environmentally friendly systems, this thesis will be focused on the development of new organometallic complexes and reactivities using earth abundant metals. In the organometallic field, the synthesis of a novel ligand bearing a chelating scaffold and a mesoionic carbene moiety has allowed the preparation of a family of first row transition metal complexes.Using carbenes as intermediates in organic synthesis, the functionalization of aromatic Csp2-H bonds and aliphatic Csp3-H bonds by the activation of diazoacetates could be developed using non-heme iron complexes.

Transition Metals in the Synthesis of Complex Organic Molecules

Synthetic Applications of Transition Metal Carbene Complexes 6.1 Introduction Carbene complexes complexes having formal metal - to - carbon double bonds are known for metals across the entire transition series , although relatively few ...

Author: Louis S. Hegedus

Publisher: University Science Books

ISBN: 9781891389047

Category: Science

Page: 358

View: 863

This second edition offers easy access to the field of organotransition metal chemistry. The book covers the basics of transition metal chemistry, giving a practical introduction to organotransition reaction mechanisms.

Transition Metal Complexes Novel Synthesis and Structure of Metal Alkylidene Complexes and Their Applications in Organic Synthesis

Possible applications of this novel catalyst are discussed.

Author: Charles Ogindo

Publisher:

ISBN: 9781470101381

Category:

Page: 150

View: 283

Ogindo's doctoral dissertation unveils a rigged metal carbene complex preparation technique that is non-cumbersome and attainable in college laboratories with no more safety concerns than already needed for the use of organolithium and main group organometallic reagents.Additionally, Ogindo uncovers a trinuclear nickel catalyst capable of trimerizing carbenes in unprecedented yields of the corresponding trimeric product. Possible applications of this novel catalyst are discussed.

Transition metal Organometallics In Organic Synthesis

Since then. transition metalcarbene complexes have attracted a great deal of attention as a novelclass of compounds, as model compounds for the study of catalytic cyclopropanation and as intermediates for organic synthesis.

Author: Howard Alper

Publisher: Elsevier

ISBN: 0323161936

Category: Science

Page: 270

View: 974

Transition Metal Organometallics in Organic Synthesis: Volume I reviews the literature in the field of organic synthesis with a focus on the most effective synthetic transformations. The text covers topics such as the general considerations in organic synthesis, C-C and C-X bond formations, and the isomerization and reorganization reactions of olefins. Also covered are topics such as displacement reactions with transition metal complexes, electrophilic reactions of organopalladium complexes, carbonylation reactions, and metal-carbene complexes — its structure, spectra, bonding, and direct synthesis. The book is recommended as a reference for chemists and inorganic chemists who would like to learn the applications of organometallic complexes as reagents and catalysts.

Science of Synthesis N Heterocyclic Carbenes in Catalytic Organic Synthesis

Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis presents the most commonly used and significant metal- or non-metal-catalyzed reactions for modern organic synthesis.

Author: S.P. Nolan

Publisher: Thieme

ISBN: 3132013315

Category: Science

Page: 846

View: 506

The field of N-heterocyclic carbenes, whether in transition-metal catalysis or organocatalysis, is rapidly evolving towards applications, but is also still very active on the catalyst development front. Significant advances have been made over the past two decades and the development of these reactions has dramatically improved the efficiency of organic synthesis. N-Heterocyclic carbene based catalysts are now widely applied in the area of synthesis of both natural products and therapeutic agents. Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis presents the most commonly used and significant metal- or non-metal-catalyzed reactions for modern organic synthesis. The basic principles and current state-of-the-art of the methods are covered. Scope, limitations, and mechanism of these reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.