Photoreceptors and Calcium

The calcium feedback signal in the phototransduction cascade of vertebrate rods. Neuron 1994; 13:849-861. Matthews HR, Murphy RLW, Fain GL et al. Photoreceptor light adaptation is mediated by cytoplasmic calcium concentration.

Author: Wolfgang Baehr

Publisher: Springer Science & Business Media

ISBN: 1461501210

Category: Medical

Page: 625

View: 958

This volume foxuses on the status of Ca2+ ions in regulation of phototransduction, light adaptation and the recovery phase in vertebrate photoreceptors. Particular emphasis is given to Ca2+-binding proteins and their targets, among them particulate guanylate cyclases, GPCR-coupled kinases and cyclic nucleotide-gated cation channels. The book also expands our understanding of events invovling Ca2+ in the retinal pigment epithelium, in synaptic transmission and secondary retinal neurons. A significant part of the book is dedicated to the role of Ca2+ in invertebrate phototransduction, the best-studied phospholipid-mediated signal transduction pathway. Several chapters explore association of gene defects with human retina disease and the generation of animal models of retinal degeneration.


Interestingly , all these photoreceptors hyperpolarize when illuminated , albeit their underlying permeability change is not necessarily to the same ion . On the other hand , the evidence for calcium's role in adaptation , which will be ...

Author: Alan Fein

Publisher: CUP Archive

ISBN: 9780521286848

Category: Medical

Page: 228

View: 610

The mechanism by which photoreceptor cells in the eyes of higher animals absorb light, giving rise to receptor potentials that initiate the visual process, is a subject of active research in biophysics today. The pace of this research and its multidisciplinary nature have made it difficult for the nonexpert to keep abreast of new discoveries. This book aims to provide a more coherent, compact summary of our knowledge about the field that has been available, serving as an up-to-date introduction to the role of photoreceptors in vision. The book is a self-contained, concise handbook for the reader who has at least a college level knowledge if cell biology, biochemistry, physical chemistry, neurobiology and physics. The authors describe the physical parameters of light and proceed to describe the mechanisms by which photoreceptors extract information about each parameter. The discussion of mechanisms is organized by discipline, following the general sequence of cellular morphology, visual pigment chemistery, and receptor physiology. Photoreceptors: their role in vision is an integrated sourcebook which will serve the novice as a 'stepping stone' to the vast and exciting scientific literature of the field.

Calcium Signaling

Calcium. Stores. in. Vertebrate. Photoreceptors. David Križaj Abstract This review lays out the emerging evidence for the fundamental role of Ca2+ stores and store-operated channels in the Ca2+ homeostasis of rods and cones.

Author: Md. Shahidul Islam

Publisher: Springer Science & Business Media

ISBN: 9400728883

Category: Medical

Page: 1267

View: 639

Calcium signaling contains a unique selection of chapters that cover a wide range of contemporary topics in this ubiquitous and diverse system of cell signaling. This book has the flavor of a primary text book, but it is much more than that. It covers topics ranging from the fundamental aspects of calcium signaling to its clinical implications, in a thoughtful and comprehensive way. It discusses cutting edge researches, and critical issues at depth, and it presents many testable hypotheses for future research. It includes the theoretical and the methodological topics as well as topics related to mathematical modeling, and simulations. If you want to read about calcium signaling in different mammalian cells, oocytes, Zebrafishes, and even in plants, in one and the same book, then this book will not disappoint you. From the beginners to the experts in the field of calcium signaling, everybody will find something useful in this very timely book.

Visual Transduction And Non Visual Light Perception

Kleinschmidt J. Signal transmission at the photoreceptor synapse. Role of calcium ions and protons. Ann N Y Acad Sci. 1991;635:468–470. Korenbrot JI, Rebrik TI. Tuning outer segment Ca2+ homeostasis to phototransduction in rods and ...

Author: Joyce Tombran-Tink

Publisher: Springer Science & Business Media

ISBN: 9781597453745

Category: Medical

Page: 509

View: 837

This book reveals not only how the eye evolved into an organ of vision, but also describes how molecular mechanisms of key molecules operate in the phototransduction cascade. In this groundbreaking text, experts also explain mechanisms for sensing radiation outside of the visible wavelengths. Comprehensive and penetrating, the book brings together the mechanisms of the visual transduction cascade and is an invaluable text for everyone conducting research in the visual system.

G Proteins and Calcium Signaling

... 33 Calcium channel , regulation of , pertussis toxinsusceptible , 13-14 Calcium movements GTP mechanism of action on ... 145-147 by light , in photoreceptors , 136–149 , see also Photoreceptors Calcium translocation , mechanism of ...

Author: Paul H. Naccache

Publisher: CRC Press

ISBN: 9780849345722

Category: Medical

Page: 170

View: 245

Calcium Signaling provides a review of the salient points of knowledge relating G proteins to calcium mobilization in a variety of cells including blood cells, (e.g. platelets, neutrophils, lymphocytes) liver, pancreas, cardiac tissue, pituitary cells, olfactory cilia, photoreceptors and the major elements of the transmembrane transduction processes is an important addition to the libraries of biological chemists, cell biologists, physiologists, pharmacologists and biophysicists among others.

Biophysics of Photoreceptors and Photomovements in Microorganisms

However, in both Chlamydomonas (Schmidt and Eckert, 1976) and Chlorogonium (Hoops and Witman, 1985) (like Euglena) a calcium-dependent change in flagellar beating (from the breast-stroke to the straight, reversed beat profile has been ...

Author: F. Lenci

Publisher: Springer Science & Business Media

ISBN: 1468459880

Category: Science

Page: 354

View: 228

This volume contains the lectures given at the NATO Advanced Study Institute on "Biophysics of Photoreceptors and Photomovements in Microorganisms" held in Tir renia (Pisa), Italy, in September 1990. The Institute was sponsored and mainly funded by the Scientific Affairs Division of NATO; the Physical Science Committee and the Institute of Biophysics of National Research Council of Italy also supported the School and substantially contributed to its success. It is our pleasant duty to thank these institu tions. Scientists from very different backgrounds contributed to the understanding of this fast developing field of research, which has seen considerable progress during the last years. The areas of expertise ranged from behavioral sciences, supported by sophi sticated techniques such as image analysis or laser light scattering, to spectroscopy, ap plied, in different time domains, to the study of the primary photoreactions, to electro physiology, biochemistry or molecular biology, with the aim of analyzing the various steps of the transduction chains and how they control the motor apparatus of the cells. The organisms studied covered a wide range, from bacteria to algae, fungi and other eukaryotes. Thus, the ASI represented a successful opportunity for carrying on and imple menting an interdisciplinary approach to the study of the biophysical basis of photore ception and photosensory transduction in aneural organisms, with special attention to the basic phenomena and the underlying molecular events. We hope that this book has caught the spirit in which the ASI was conceived.

Vision in Vertebrates

The presence of calcium and the enzymes regulating cyclic nucleotide levels (cyclase, phosphodiesterase) in photoreceptor outer segments have been demonstrated ultracytochemically (see Athanassious, 1983). A key feature of the internal ...

Author: M. A. Ali

Publisher: Springer Science & Business Media

ISBN: 1468491296

Category: Medical

Page: 272

View: 382

When Dr. Katherine Tansley's "Vision in Vertebrates" appeared in 1965, it filled a real void that had hitherto existed. It did so by serving at once as a text-book: for an undergraduate course, a general introduction to the subject for post-graduate students embarking on research on some aspect of vision, and the interested non-specialists. Gordon Walls' "The Vertebrate Eye and It. s Adaptive Radiation" and A. Rochon-Duvigneaud's "Les Yeux et la Vision des Vertebres" have served as important sources of information on the subject and continue to do so even though it is 40 years since they appeared. However, they are essentially specialised reference works and are not easily accessible to boot. The genius of Katherine Tansley was to present in a succinct (132 pages) and lucid way a clear and an interesting survey of the matter. Everyone liked it, particularly the students because one could read it quickly and understand it. Thus, when it seemed that a new edition was desirable, especially in view of the enormous strides made and the vast literature that had accumulated in the past 20 years, one of us (MAA) asked Dr. Tansley if she would undertake the task. Since she is in retirement and her health not in a very satisfactory state both she and her son, John Lythgoe (himself a specialist of vision), asked us to take over the task.

New Scientist

When they added calcium buffers, which oppose changes in the concentration of calcium, the initial response of the photoreceptor to light was unchanged, a result which indicates that calcium alone cannot be responsible for closing ...





Page: 72

View: 366

New Scientist magazine was launched in 1956 "for all those men and women who are interested in scientific discovery, and in its industrial, commercial and social consequences". The brand's mission is no different today - for its consumers, New Scientist reports, explores and interprets the results of human endeavour set in the context of society and culture.