The Chemistry of Organolithium Compounds

The fourth part considers the synthesis of organometallic compound derivatives from main group and transition metals. This book will prove useful to organic chemists and organic chemistry researchers.

Author: B. J. Wakefield

Publisher: Elsevier

ISBN: 1483278700

Category: Science

Page: 348

View: 635

The Chemistry of Organolithium Compounds is a comprehensive review of the status of organolithium compound chemistry. This book is composed of four parts and nineteen chapters that particularly describe the reactions involving these compounds The first part highlights the constitution of organolithium compounds, specifically in the absence and presence of electron donors, as well as the configurational stability of these compounds. The second part deals with their preparation from organic halides and lithium metal involving metallation and metal-halogen exchange, while the third part focuses on their organic synthesis. The fourth part considers the synthesis of organometallic compound derivatives from main group and transition metals. This book will prove useful to organic chemists and organic chemistry researchers.

The Chemistry of Organolithium Compounds

This is the first volume in the series to concentrate on organo-lithium compounds - the sub series "The chemistry of the metal-carbon bond" (5 vol) treated organometallics in general.

Author: Zvi Rappoport

Publisher: John Wiley & Sons

ISBN: 0470021101

Category: Science

Page: 1400

View: 489

This is the first volume in the series to concentrate on organo-lithium compounds - the sub series "The chemistry of the metal-carbon bond" (5 vol) treated organometallics in general. It deals with theoretical/physical/computational apsects, as well as major spectroscopies, such as MS, NMR, IR/UV etc and both biological and industrial applications. The core of the volume is the synthetic chapters with lots of examples for modern synthetic approaches Written by key researchers in the field An invaluable reference source to organic chemists working in academia and industry Features important reagents in organic synthesis


The Chemistry of Organolithium Compounds

All new titles will be published online and a growing list of older titles is added every year. It is the ultimate goal that all titles published in the Patai Series will be available in electronic format.

Author: Zvi Rappoport

Publisher: John Wiley & Sons

ISBN: 0470023228

Category: Science

Page: 768

View: 844

Patai Series: The Chemistry of Functional Groups A series of advanced treatises founded by Professor Saul Patai and under the general editorship of Professor Zvi Rappoport The Patai Series publishes comprehensive reviews on all aspects of specific functional groups. Each volume contains outstanding surveys on theoretical and computational aspects, NMR, MS, other spectroscopical methods and analytical chemistry, structural aspects, thermochemistry, photochemistry, synthetic approaches and strategies, synthetic uses and applications in chemical and pharmaceutical industries, biological, biochemical and environmental aspects. To date, over 100 volumes have been published in the series. Recently Published Titles * The chemistry of the Cyclopropyl Group (Volume 2) * The chemistry of the Hydrazo Azo and Azozy Groups (Volume 2, 2 parts) * The chemistry of Double-Bonded Functional Groups (Volume 3, 2 parts) * The chemistry of Organophosphorus Compounds (Volume 4) * The chemistry of Halides, Pseudo-Halides and Azides (Volume 2, 2 parts) * The chemistry of the Amino, Nitro and Nitroso Groups (2 volumes, 2 parts) * The chemistry of Dienes and Polyenes (2 volumes) * The chemistry of Organic Derivatives of Gold and Silver * The chemistry of Organic Silicon Compounds (2 volumes, 4 parts) * The chemistry of Organic Germanium, Tin and Lead Compounds (Volume 2, 2 parts) * The chemistry of Phenols (2 parts) * The chemistry of Organolithium Compounds (2 parts) * The chemistry of Cyclobutanes (2 parts) * Forthcoming Titles * The chemistry of Peroxides (Volume 2, 2 parts) * The chemistry of Organozinc Compounds * The chemistry of Anilines The Patai Series Online The Patai Series is available in electronic format on Wiley InterScience. All new titles will be published online and a growing list of older titles is added every year. It is the ultimate goal that all titles published in the Patai Series will be available in electronic format.



Chemistry of Organolithium Compounds and Acetylenes

A brief summary of the research is presented. Primary organolithium compounds react with diphenylacetylene to produce an addition-metalation product.

Author: James E. Mulvaney

Publisher:

ISBN:

Category:

Page: 6

View: 432

A brief summary of the research is presented. Primary organolithium compounds react with diphenylacetylene to produce an addition-metalation product. Depending upon conditions tertiary organolithium compounds give addition-metalation or products of electron transfer. Using methylphenylacetylenes and organolithium compounds one obtains a trimetalated product, N, N, N, N-Tetramethylethylene diamine has a large accelerating effect on the rate of these reactions. Lithium metal, asinitiator, has been found to give unusual copolymer compositions with acrylophenones and styrenes. The significance of these results are discussed. (Author).

The Chemistry of Peroxides Parts 1 and 2 2 Volume Set

This series covers all aspects of organic chemistry with each volume containing chapters on: General and theoretical aspects Computational approaches Thermodynamics and kinetics NMR and ESR Mass Spectrometry Spectroscopies Analytical ...

Author:

Publisher: John Wiley & Sons

ISBN: 0470862750

Category: Science

Page: 1518

View: 363

The Chemistry of Peroxides is a new volume in the Chemistry of Functional Groups series. This series covers all aspects of organic chemistry with each volume containing chapters on: General and theoretical aspects Computational approaches Thermodynamics and kinetics NMR and ESR Mass Spectrometry Spectroscopies Analytical aspects Reaction mechanisms Syntheses Biological effects Environmental effects Industrial applications Edited by Zvi Rappoport, this series provides outstanding reviews on all aspects of functional groups in analytical, physical, synthetic and applied chemistry.

Stereochemical Aspects of Organolithium Compounds

Selectivity, Strategy, and Efficiency in Modern Organic Chemistry, ... Gawley, R. E.; Coldham, I. In The Chemistry of Organolithium Compounds (Patai Series) ...

Author: Robert E. Gawley

Publisher: John Wiley & Sons

ISBN: 3906390632

Category: Science

Page: 305

View: 223

Topics in Stereochemistry, previously edited by "the father of stereochemistry" Ernest L. Eliel, is a longstanding, successful series covering the most important advances in the field. The much-anticipated Volume 26 on stereochemical aspects of organolithium compounds includes chapters on the following topics: * Asymmetric Deprotonations Using Chiral Lithium Amide Bases * Self-Regeneration of Stereocenters (SRS) via Stereolabile Axially Chiral Intermediates * Overview of Carbanion Dynamics and Electrophilic Substitutions in Chiral Organolithium Compounds * Oxiranyllithiums as Chiral Synthons for Asymmetric Synthesis * Test on the Configurational Stability/Lability of Organolithium Compounds * Mechanism and Stereochemical Features in Asymmetric Deprotonation Using RLi/(-)-Sparteine Bases * Dynamic Resolutions of Chiral Organolithiums Volume 26 of Topics in Stereochemistry marks the end of an era, while developing a bridge to the next generation. A new generation in publishing, parallel to a new generation in Stereochemistry mandated a new venue and modus operandi for Topics. Zurich, the home of Werner and Wislicenus, has a unique heritage in Stereochemistry. Fortunately, the Wiley family's publishing partnerships include Verlag Helvetica Chimica Acta, a house with a reputation for superior quality in publishing. Indeed, within the pages of its namesake periodical, Helvetica Chimica Acta, one finds many of the seminal research works of stereochemistry's giants. As such, a transfer of editorial operations to Zurich and a collaboration bringing Topics as a series closer to periodical status provides a growth platform for the future.

The Chemistry of Organozinc Compounds

The Patai Series publishes comprehensive reviews on all aspects of specific functional groups.

Author: Zvi Rappoport

Publisher: John Wiley & Sons

ISBN: 0470093382

Category: Science

Page: 1140

View: 998

The Patai Series publishes comprehensive reviews on all aspects of specific functional groups. Each volume contains outstanding surveys on theoretical and computational aspects, NMR, MS, other spectroscopic methods and analytical chemistry, structural aspects, thermochemistry, photochemistry, synthetic approaches and strategies, synthetic uses and applications in chemical and pharmaceutical industries, biological, biochemical and environmental aspects. To date, over 110 volumes have been published in the series. Recently Published Titles The chemistry of the Cyclopropyl Group (Volume 2) The chemistry of the Hydrazo, Azo and Azoxy Groups (Volume 2, 2 parts) The chemistry of Double-Bonded Functional Groups (Volume 3, 2 parts) The chemistry of Organophosphorus Compounds (Volume 4) The chemistry of Halides, Pseudo-Halides and Azides (Volume 2, 2 parts) The chemistry of the Amino, Nitro and Nitroso Groups (2 volumes, 2 parts) The chemistry of Dienes and Polyenes (2 volumes) The chemistry of Organic Derivatives of Gold and Silver The chemistry of Organic Silicon Compounds (2 volumes, 4 parts) The chemistry of Organic Germanium, Tin and Lead Compounds (Volume 2, 2 parts) The chemistry of Phenols (2 parts) The chemistry of Organolithium Compounds (2 volumes, 3 parts) The chemistry of Cyclobutanes (2 parts) The chemistry of Peroxides (Volume 2, 2 parts) The chemistry of Organozinc Compounds (2 parts) Forthcoming Titles The chemistry of Anilines The chemistry of Organomagnesium Compounds The Patai Series Online The Patai Series is available in electronic format on Wiley InterScience. All new titles will be published as online books and a growing list of older titles will be added every year. It is the ultimate goal that all titles published in the Patai Series will be available in electronic format. For more information see under Online Books on: www.interscience.wiley.com

The Chemistry of Function Groups 6 Volume Set

A comprehensive, six-component set on the chemistry of function groups This set includes: The Chemistry of Organolithium Compounds, The Chemistry of Organozinc Compounds: R-Zn, The Chemistry of Peroxides, Parts 1 and 2, The Chemistry of ...

Author: Zvi Rappoport

Publisher: Wiley

ISBN: 9780470779521

Category: Science

Page: 7272

View: 440



The Chemistry of Organomagnesium Compounds 2 Volume Set

Since the area of Organomagnesium Chemistry continues to grow far beyond the classical Grignard Reagents, this is an essential resource to help the reader keep abreast of the latest developments.

Author: Zvi Rappoport

Publisher: John Wiley & Sons

ISBN: 047075186X

Category: Science

Page: 920

View: 226

Magnesium remains almost unique among the metals in its ability to react directly with a wide variety of compounds. This organic chemistry field has seen steady progress, and a volume on this topic is long overdue. In the tradition of the Patai Series this title treats all aspects of functional groups, containing chapters on the theoretical and computational foundations; on analytical and spectroscopic aspects with dedicated chapters on Mass Spectrometry, NMR, IR/UV, etc.; on reaction mechanisms; on applications in syntheses. Depending on the functional group there are also chapters on industrial use, on effects in biological and/or environmental systems. Since the area of Organomagnesium Chemistry continues to grow far beyond the classical Grignard Reagents, this is an essential resource to help the reader keep abreast of the latest developments.

Lithium Chemistry

Supported by nearly two hundred illustrations, this book draws uponthe expertise of prominent researchers in the field, and treats thefull range of modern applications and techniques.

Author: Anne-Marie Sapse

Publisher: John Wiley & Sons

ISBN: 9780471549307

Category: Science

Page: 595

View: 939

An up-to-date, comprehensive guide to LITHIUM CHEMISTRY Although lithium has been the subject of numerous individualstudies, this intriguing element has rarely been examined from thebroad perspective many researchers require. Lithium Chemistry: ATheoretical and Experimental Overview fills this void by providingthe most thorough and up-to-date overview available of currenttheories and experimental data. Supported by nearly two hundred illustrations, this book draws uponthe expertise of prominent researchers in the field, and treats thefull range of modern applications and techniques. The result is aunique and invaluable guide to lithium studies for researchers andgraduate students working in the fields of organic, inorganic, andorgano-metallic chemistry. Lithium Chemistry: A Theoretical and Experimental Overview assumesa background in quantum chemistry and experimental physicalchemistry at the graduate level and includes coverage of thesemajor topics: * Bonding, structures, and energies in organolithium compounds * Theoretical studies of aggregates of lithium compounds * Comparison of lithium and hydrogen bonds * Lithium atom matrix reactions with small molecules * NMR of organolithium compounds * Aspects of the thermochemistry of lithium compounds * The structure of lithiated amines and lithiated ethers--fromcarbanions to carbenoids * Complexes of inorganic lithium salts * Structures of lithium salts of heteroatom compounds * Synthetic ionophores for lithium ions


Comprehensive Organic Functional Group Transformations Synthesis carbon with one heteroatom attached by a single bond

551 B. J. Wakefield ; “ The Chemistry of Organolithium Compounds , ” Pergamon Press , Oxford , 1974 . 653 J. L. Wardell ; in “ The Chemistry of the Thiol ...

Author: Alan R. Katritzky

Publisher: Elsevier

ISBN: 9780080423234

Category: Science

Page: 8878

View: 737

This Volume covers the formation of carbon-carbon single-, double- and triple bonds by substitution and addition reactions as well as by various rearrangements. The formation of carbon-carbon multiple bonds by elimination and condensation procedures is fully documented. In addition the synthesis of carbon-hydrogen bonds principally by substitution and addition reactions is featured as is the preparation of a wide variety of carbon-centred anions, cations and radicals.

Process Chemistry in the Pharmaceutical Industry Volume 2

(d) Wakefield, B.J., The Chemistry of Organolithium Compounds, Pergamon Press, New York, 1974. (e) Wardell, J.L., Comprehensive Organometallic Chemistry, ...

Author: Kumar Gadamasetti

Publisher: CRC Press

ISBN: 9781420008357

Category: Science

Page: 520

View: 626

As pharmaceutical companies strive to develop safer medicines at a lower cost, they must keep pace with the rapid growth of technology and research methodologies. Defying the misconception of process chemistry as mere scale-up work, Process Chemistry in the Pharmaceutical Industry, Vol. 2: Challenges in an Ever Changing Climate explores novel applications of synthetic, physical, and analytical chemistry in drug discovery and development. It offers an accurate depiction of the most up-to-date process research and development methods applied to synthesis, clinical trials, and commercializing drug candidates. The second installment in this progressive series, this volumereviews the latest breakthroughs to advance process chemistry, including asymmetric synthesis, crystallization, morphology, enzymatic intervention, green chemistry, macromolecules (monoclonal antibodies, biological molecules, polymers), enantioselectivity, organometallic chemistry, process analytical tools, chemical engineering controls, regulatory compliance, and outsourcing/globalization. It explores new approaches to synthetic processes, examines the latest safety methods and experiment design, and suggests realistic solutions to problems encountered in manufacturing and process development. Significant topics include atom economy, ease of synthesis, instrumentation, automization, quality control, cost considerations, green practices, and future trends. Jointly edited by the founder/president of Delphian Pharmaceuticals and the director of Chemical R&D at Pfizer, this book brings together contributions byreputed scientists, technologists, engineers, and professors from leading academic institutions, such as the Imperial College, UK, the University of Tokyo, ETH, Switzerland, the International University at Bermen, Germany, and the University of Connecticut, USA, and from principal pharmaceutical companies that include Merck, Bristol Myers Squibb, Pfizer, Novartis, Eli Lilly, Astrazeneca and DSM.



The Chemistry of Metal Enolates

Other applications for metal enolates, such as their use in forming metal coatings, are also discussed. This volume extends and complements the previous volume 1, which was published in 2009.

Author: Jacob Zabicky

Publisher: John Wiley & Sons

ISBN: 111908329X

Category: Science

Page: 592

View: 492

PATAI's Chemistry of Functional Groups publishes comprehensive reviews on all aspects of specific functional groups. Each volume contains outstanding surveys on theoretical and computational aspects, NMR, MS, other spectroscopic methods and analytical chemistry, structural aspects, thermochemistry, photochemistry, synthetic approaches and strategies, synthetic uses and applications in chemical and pharmaceutical industries, biological, biochemical and environmental aspects. To date, over 140 volumes have been published in the series. Metal enolates form a class of compounds that have recently received much attention because of their part in the selective formation of carbon-carbon bonds via the aldol reaction. Other applications for metal enolates, such as their use in forming metal coatings, are also discussed. This volume extends and complements the previous volume 1, which was published in 2009.