The Compatibility Gene

The Compatibility Gene takes readers on a global journey of discovery spanning 60 years, involving scores of scientists, and encompassing the history of transplants and immunology.

Author: Daniel Michael Davis

Publisher: Oxford University Press, USA

ISBN: 0199316414

Category: Medical

Page: 250

View: 978

The Compatibility Gene takes readers on a global journey of discovery spanning 60 years, involving scores of scientists, and encompassing the history of transplants and immunology. That journey has revealed astonishing links between who we are as individuals and our never-ceasing struggle to survive disease. Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease. In The Compatibility Gene, distinguished immunologist Daniel Davis draws on new research to suggest a number of even more fascinating-and controversial-conclusions about compatibility genes: that we find others more or less sexy according to their compatibility genes (dating services are starting to match people in this way); that the wiring between some neurons is kept or broken according to the activity of compatibility genes; and that compatibility genes influence the chances of a couple having a successful pregnancy. Profoundly personal, life-forming and life-changing decisions appear to be governed by the actions of a few inherited genes. Most importantly, Davis proposes that because we each respond slightly differently to any particular disease, in the not-too-distant future vaccines and other medications may be tailored to match our compatibility genes, a revolutionary breakthrough in the fight against disease. Including vivid portraits of the scientists who worked tirelessly to unlock the secrets of compatibility genes, as well as patients who survived disease due to lucky genetic inheritances, The Compatibility Gene explains an aspect of human biology that will undoubtedly have profound impacts on medical practice in the 21st Century.

The Compatibility Gene

Short-listed for the Society of Biology Book Award 2014 Long-listed for the Royal Society Winton prize for science books 2014 In The Compatibility Gene, leading scientist Daniel M Davis tells the story of the crucial genes that define our ...

Author: Daniel M Davis

Publisher: National Geographic Books

ISBN: 0241956757

Category: Science

Page: 0

View: 251

Short-listed for the Society of Biology Book Award 2014 Long-listed for the Royal Society Winton prize for science books 2014 In The Compatibility Gene, leading scientist Daniel M Davis tells the story of the crucial genes that define our relationships, our health and our individuality. We each possess a similar set of around 25,000 human genes. Yet a tiny, distinctive cluster of these genes plays a disproportionately large part in how our bodies work. These few genes, argues Davis, hold the key to who we are as individuals and our relationship to the world: how we combat disease, how our brains are wired, how attractive we are, even how likely we are to reproduce. The Compatibility Gene follows the remarkable history of these genes' discovery. From the British scientific pioneers who struggled to understand the mysteries of transplants to the Swiss zoologist who devised a new method of assessing potential couples' compatibility based on the smell of worn T-shirts, Davis traces a true scientific revolution in our understanding of the human body: a global adventure spanning some sixty years. 'Unusual results, astonishing implications and ethical dilemmas' The Times 'Packed with an insider's knowledge' New York Times 'He makes immunology as fascinating to popular science readers as cosmology, consciousness, and evolution' Steven Pinker 'An elegantly written, unexpectedly gripping account' Bill Bryson Guardian, Books of the Year Daniel M Davis is director of research at the University of Manchester's Collaborative Centre for Inflammation Research and a visiting professor at Imperial College, London. He has published over 100 academic articles, including papers in Nature and Science, and Scientific American. He has won the Oxford University Press Science Writing Prize and given numerous interviews for national and international media. He was elected a Fellow of the Academy of Medical Sciences in 2011.

The Compatibility Gene

Blood-group genes come in just three versions – such human differences are simple compared to the immense variation in our compatibility genes that control skin graft success. Recall that these genes vary the most from person to person.

Author: Daniel M Davis

Publisher: Penguin UK

ISBN: 0141972521

Category: Science

Page: 256

View: 175

The Compatibility Gene is a scientific adventure story set in a new field of genetic discovery - that of the crucial genes that define our relationships, our health and our individuality. Here, Daniel M Davis, one of the leading scientists in the field, tells us the story of its groundbreaking developments that have the potential to change us all We each possess a similar set of around 25,000 human genes. Yet a tiny, distinctive cluster of these genes plays a disproportionately large part in how our bodies work. These few genes, argues Daniel M. Davis, hold the key to who we are as individuals and our relationship to the world: how we combat disease, how our brains are wired, how attractive we are, even how likely we are to reproduce. In The Compatibility Gene, one of our foremost immunologists tells the remarkable history of these genes' discovery and the unlocking of their secrets. From the British scientific pioneers who, during the Second World War, struggled to understand the mysteries of transplants and grafts, to the Swiss zoologist who devised an entirely new method of assessing potential couples' compatibility based on the smell of worn T-shirts, Davis traces what is nothing less than a scientific revolution in our understanding of the human body: a global adventure spanning some sixty years. Davis shows how the compatibility gene is radically transforming our knowledge of the way our bodies work - and is having profound consequences for medical research and ethics. Looking to the future, he considers the startling possibilities of what these wondrous discoveries might mean for you and me. Who am I? What makes me different from everyone else? Daniel Davis recounts the remarkable science that has answered one version of these questions. 'He makes immunology as fascinating to popular science readers as cosmology, consciousness, and evolution' Steven Pinker, Johnstone Professor of Psychology, Harvard University, and the author of How the Mind Works and The Better Angels of Our Nature 'Davis weaves a warm biographical thread through his tale of scientific discovery, revealing the drive and passion of those in the vanguard of research ... unusual results, astonishing implications and ethical dilemmas' The Times 'Davis makes the twists and turns all count' Guardian 'A fascinating, expertly told story' Michael Brooks, New Statesman Daniel M. Davis is director of research at the University of Manchester's Collaborative Centre for Inflammation Research and a visiting professor at Imperial College, London. He has published over 100 academic papers, including papers in Nature and Science, and Scientific American, and lectures all over the world, including at the Royal Institution. He has previously won the Oxford University Press Science Writing Prize, and has given numerous interviews for national and international media, including the Times, Guardian, Metro, and National Public Radio (USA). A major feature on his research was published in The Times. Experiments filmed in his laboratory were shown in the BBC series 'The History of Medicine' (2008). He also keenly engages in broad scientific affairs, recently publishing a view on UK science funding policies in Nature.

The Compatibility Gene

"There are far-reaching consequences from the way our body has evolved to fight disease. This book describes how genes link our struggle with disease to compatibility with others, the wiring of our brain and success in pregnancy.

Author: Daniel Michael Davis

Publisher: Oxford University Press, USA

ISBN: 9780199393930

Category: Medical

Page: 248

View: 932

"There are far-reaching consequences from the way our body has evolved to fight disease. This book describes how genes link our struggle with disease to compatibility with others, the wiring of our brain and success in pregnancy."--Publisher information.

The Secret Body

The Secret Body reveals how these and other stunning breakthroughs and technologies are transforming our understanding of how the human body works, what it is capable of, how to protect it from disease, and how we might manipulate it in the ...

Author: Daniel M. Davis

Publisher: Princeton University Press

ISBN: 0691242127

Category: Science

Page: 224

View: 735

“A perfect blend of cutting-edge science and compelling storytelling.”—Bill Bryson A revolutionary new vision of human biology and the scientific breakthroughs that will transform our lives Imagine knowing years in advance whether you are likely to get cancer or having a personalized understanding of your individual genes, organs, and cells. Imagine being able to monitor your body's well-being, or have a diet tailored to your microbiome. The Secret Body reveals how these and other stunning breakthroughs and technologies are transforming our understanding of how the human body works, what it is capable of, how to protect it from disease, and how we might manipulate it in the future. Taking readers to the cutting edge of research, Daniel Davis shows how radical new possibilities are becoming realities thanks to the visionary efforts of scientists who are revealing the invisible and secret universe within each of us. Focusing on six important frontiers, Davis describes what we are learning about cells, the development of the fetus, the body's immune system, the brain, the microbiome, and the genome—areas of human biology that are usually understood in isolation. Bringing them together here for the first time, Davis offers a new vision of the human body as a biological wonder of dizzying complexity and possibility. Written by an award-winning scientist at the forefront of this adventure, The Secret Body is a gripping drama of discovery and a landmark account of the dawning revolution in human health.

The Beautiful Cure

In The Beautiful Cure, leading immunologist Daniel M. Davis describes how the scientific quest to understand how the immune system works—and how it is affected by stress, sleep, age, and our state of mind—is now unlocking a ...

Author: Daniel M. Davis

Publisher: University of Chicago Press

ISBN: 022637114X

Category: Medical

Page: 271

View: 382

“Visceral.”—Wall Street Journal “Illuminating.”—Publishers Weekly “Heroic.”—Science The immune system holds the key to human health. In The Beautiful Cure, leading immunologist Daniel M. Davis describes how the scientific quest to understand how the immune system works—and how it is affected by stress, sleep, age, and our state of mind—is now unlocking a revolutionary new approach to medicine and well-being. The body’s ability to fight disease and heal itself is one of the great mysteries and marvels of nature. But in recent years, painstaking research has resulted in major advances in our grasp of this breathtakingly beautiful inner world: a vast and intricate network of specialist cells, regulatory proteins, and dedicated genes that are continually protecting our bodies. Far more powerful than any medicine ever invented, the immune system plays a crucial role in our daily lives. We have found ways to harness these natural defenses to create breakthrough drugs and so-called immunotherapies that help us fight cancer, diabetes, arthritis, and many age-related diseases, and we are starting to understand whether activities such as mindfulness might play a role in enhancing our physical resilience. Written by a researcher at the forefront of this adventure, The Beautiful Cure tells a dramatic story of scientific detective work and discovery, of puzzles solved and mysteries that linger, of lives sacrificed and saved. With expertise and eloquence, Davis introduces us to this revelatory new understanding of the human body and what it takes to be healthy.

The Beautiful Cure

Describes the scientific quest to understand how the immune system works - and how it is affected by stress, sleep, age and our state of mind

Author: Daniel M. Davis

Publisher: Jonathan Cape

ISBN: 9781847923745

Category: Health

Page: 272

View: 562

'Thrilling ... Reads like the best kind of adventure story' STEPHEN FRY 'Wonderful ... recounts in exceptionally clear and sympathetic prose how research into the immune system has resulted in a health revolution' HENRY MARSH, New Statesman SHORTLISTED FOR THE ROYAL SOCIETY SCIENCE BOOK PRIZE A Best Book of the Year 2018 in The Times, Telegraph & New Scientist The immune system holds the key to human health. In The Beautiful Cure, leading immunologist Professor Daniel Davis describes the scientific quest to understand how it works - and how it is affected by stress, sleep, age and our state of mind - and explains how this knowledge is now unlocking a revolutionary new approach to medicine and well-being. The body's ability to fight disease and heal itself is one of the great mysteries and marvels of nature. But within the last few years painstaking research has resulted in major advances in our understanding of this breathtakingly beautiful inner world: a vast and intricate network of specialist cells, regulatory proteins and dedicated genes that are continually protecting our bodies. Far more powerful than any medicine ever invented, it also plays a crucial role in our daily lives. Already we have found ways to harness these natural defences to create breakthrough drugs and so-called immunotherapies that help us fight cancer, diabetes, arthritis and many age-related diseases, and we are starting to understand whether or not activities such as mindfulness might play a role in enhancing our physical resilience. Written by an expert at the forefront of this adventure, The Beautiful Cure tells a dramatic story of detective work and discovery, of puzzles solved and of the mysteries that remain, of lives sacrificed and saved, introducing the reader to this revelatory new understanding of the human body and what it takes to be healthy.

Immunity The Science of Staying Well

Let's call these genes the 'compatibility' genes for short. Our compatibility genes encode our immunity, yet they are as changeable as the pathogens (bacteria or viruses) they aim to prevent. These molecules have evolved to come in a ...

Author: Dr Jenna Macciochi

Publisher: HarperCollins UK

ISBN: 0008370273

Category: Health & Fitness

Page: 352

View: 523

Start strengthening your immunity for good.

Chinese Journal of Genetics

The ste nility in the cross of Akihikara and IR 24 was controlled by both S - 5 and S - p ( t ) , and the two S genes had the additive effect . à KEY WORDS : Oryza sativa ; indica japonica cross ; Sterility ; Wide compatibility gene ...

Author:

Publisher:

ISBN:

Category: Genetics

Page:

View: 367


The Beautiful Cure

The Beautiful Cure tells a dramatic story of detective work and discovery, of puzzles solved and of the mysteries that remain, and of lives sacrificed and saved.

Author: Daniel M. Davis

Publisher: Bodley Head Childrens

ISBN: 9781847923738

Category: Health

Page: 272

View: 963

The immune system holds the key to human health. In "The Beautiful Cure", leading immunologist Daniel Davis describes the scientific quest to understand how it works - and how it is affected by stress, sleep, age and our state of mind - and explains how this knowledge is now unlocking a revolutionary new approach to medicine and well-being. The body's ability to fight disease and heal itself is one of the great mysteries and marvels of nature, but within the last few years painstaking research has resulted in major advances in our understanding of the immune system, revealing an inner world of breath-taking sophistication, complexity and beauty. Far more powerful than any medicine ever invented, it also plays a crucial role in our daily lives. Already we have found ways to harness these natural defences to create break-through drugs and therapies that help us fight cancer, diabetes, arthritis and many age-related diseases, and we are starting to understand whether or not activities such as mindfulness might play a role in enhancing our physical resilience.